Drug Interaction Report

Talk to your doctor before using diclofenac topical together with sulindac. Both of these medications are considered nonsteroidal anti-inflammatory drugs. Since the medication in diclofenac topical may be absorbed from the skin, combining it with sulindac may increase the risk and/or severity of side effects reported with this class of drugs, including stomach ulcer, fluid retention, high blood pressure, bleeding, and liver or kidney problems. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Ask your doctor before using sulindac together with ethanol (alcohol). Do not drink alcohol while taking sulindac. Alcohol can increase your risk of stomach bleeding caused by sulindac. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.