Drug Interaction Report
4 potential interactions and/or warnings found for the following 2 drugs:
- Cotrim Pediatric (sulfamethoxazole / trimethoprim)
- folic acid
Interactions between your drugs
sulfamethoxazole folic acid
Applies to: Cotrim Pediatric (sulfamethoxazole / trimethoprim), folic acid
Sulfamethoxazole may decrease the blood levels and effects of folic acid and if you take pyrimethamine to treat malaria, high doses of folic acid may interfere with its antimalarial effects. Your doctor may be able to prescribe alternatives that do not interact, or you may need more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
trimethoprim folic acid
Applies to: Cotrim Pediatric (sulfamethoxazole / trimethoprim), folic acid
Trimethoprim may decrease the blood levels and effects of folic acid and if you take pyrimethamine to treat malaria, high doses of folic acid may interfere with its antimalarial effects. Your doctor may be able to prescribe alternatives that do not interact, or you may need more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
folic acid food
Applies to: folic acid
Talk to your doctor before using alcohol together with folic acid. Excessive consumption of alcohol may reduce the absorption and increase the elimination of folic acid. Contact your doctor if your symptoms worsen or your condition changes. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
sulfamethoxazole food
Applies to: Cotrim Pediatric (sulfamethoxazole / trimethoprim)
Ask your doctor before using sulfamethoxazole together with ethanol (alcohol). Contact your doctor if you experience unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, or vomiting. If you experience these side effects, you may need to avoid ethanol (alcohol) while taking sulfamethoxazole. You should check your food and medicine labels to see if these products contain ethanol (alcohol). It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
See also:
Augmentin
Augmentin is a prescription antibiotic combining amoxicillin and clavulanate to treat bacterial ...
Bactrim
Bactrim (sulfamethoxazole and trimethoprim) is an antibiotic used to treat ear infections, urinary ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Keflex
Keflex (cephalexin) is used to treat infections caused by bacteria, including respiratory ...
Macrobid
Macrobid (nitrofurantoin) is an antibiotic used to treat urinary tract infections. Includes side ...
Cipro
Cipro (ciprofloxacin) is a fluoroquinolone antibiotic used to treat bacterial infections. Learn ...
Zithromax
Zithromax (azithromycin) treats infections caused by bacteria, such as respiratory infections, skin ...
Mucinex
Mucinex (guaifenesin) is used to relieve the symptoms of cough and loosen mucus in the chest ...
Flagyl
Flagyl is used to treat bacterial infections of the vagina, stomach, skin and joints. Learn about ...
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.