Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- sulfadiazine
- Uro-Pain Dual Action (methenamine / sodium salicylate)
Interactions between your drugs
methenamine sulfADIAZINE
Applies to: Uro-Pain Dual Action (methenamine / sodium salicylate), sulfadiazine
CONTRAINDICATED: Some sulfonamides can form an insoluble precipitate with formaldehyde, which is generated from the hydrolysis of methenamine in acidic urine maintained by the presence of hippuric acid.
MANAGEMENT: Methenamine preparations should not be given to patients taking sulfonamides due to the risk of crystalluria. An alkalinizing agent should not be added because this may render methenamine less effective.
References (2)
- (2001) "Product Information. Urised (methenamine)." Polymedica Pharmaceuticals USA Inc
- (2002) "Product Information. Hiprex (methenamine)." Hoechst Marion Roussel
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Report options
- Switch to consumer interaction data
- Email this report to a friend, doctor, or patient
- Ask questions, find answers
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Bactrim
Bactrim (sulfamethoxazole and trimethoprim) is an antibiotic used to treat ear infections, urinary ...
Zithromax
Zithromax (azithromycin) treats infections caused by bacteria, such as respiratory infections, skin ...
Botox
Botox is used to treat chronic migraines, excessive sweating, bladder conditions, eye muscle ...
Azithromycin Dose Pack
Azithromycin Dose Pack is used for babesiosis, bacterial endocarditis prevention, bacterial ...
Cleocin
Cleocin (clindamycin) is used to treat serious bacterial infections. Includes Cleocin side effects ...
Biaxin
Biaxin is used for bacterial endocarditis prevention, bronchitis, dental abscess, helicobacter ...
SMZ-TMP DS
SMZ-TMP DS (sulfamethoxazole and trimethoprim) is an antibiotic used to treat ear infections ...
Penicillin VK
Penicillin VK is used for bacterial infection, clostridioides difficile infection, cutaneous ...
Co-trimoxazole
Co-trimoxazole is used for bacterial infection, bacterial skin infection, bronchitis ...
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.