Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- ranitidine bismuth citrate
- Risperdal M-Tab (risperidone)
Interactions between your drugs
risperiDONE raNITIdine bismuth citrate
Applies to: Risperdal M-Tab (risperidone), ranitidine bismuth citrate
Coadministration of risperidone with cimetidine or ranitidine may marginally increase the bioavailability of risperidone. The mechanism and clinical significance are unknown. According to the manufacturer, dose modifications are not required.
References (4)
- (2005) "Product Information. Risperdal Consta (risperidone)." Janssen Pharmaceuticals
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
- Canadian Pharmacists Association (2006) e-CPS. http://www.pharmacists.ca/function/Subscriptions/ecps.cfm?link=eCPS_quikLink
- Cerner Multum, Inc. "Australian Product Information."
Drug and food interactions
risperiDONE food
Applies to: Risperdal M-Tab (risperidone)
GENERALLY AVOID: Risperidone oral solution is not compatible with either tea or cola. In addition, alcohol may potentiate some of the pharmacologic effects of risperidone. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.
MANAGEMENT: Risperidone oral solution should not be mixed with tea or cola. It may be taken with water, coffee, orange juice, or lowfat milk. Patients should also be advised to avoid consumption of alcohol.
References (1)
- (2001) "Product Information. Risperdal (risperidone)." Janssen Pharmaceuticals
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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