Drug Interaction Report
6 potential interactions and/or warnings found for the following 2 drugs:
- Prevpac (amoxicillin / clarithromycin / lansoprazole)
- rifampin
Interactions between your drugs
rifAMPin clarithromycin
Applies to: rifampin, Prevpac (amoxicillin / clarithromycin / lansoprazole)
Ask your doctor before using rifAMPin together with clarithromycin. This can alter your blood levels or add to the side effects of either medication. Call the doctor if you have side effects such as nausea, vomiting and diarrhea. This combination can also affect the eye and cause inflammation of part or all of the uvea, the middle part of the eye. You may need a dose adjustment or special tests to safely take both medications together. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
rifAMPin lansoprazole
Applies to: rifampin, Prevpac (amoxicillin / clarithromycin / lansoprazole)
RifAMPin may reduce the blood levels and effects of lansoprazole. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
clarithromycin lansoprazole
Applies to: Prevpac (amoxicillin / clarithromycin / lansoprazole), Prevpac (amoxicillin / clarithromycin / lansoprazole)
Clarithromycin may increase the blood levels and side effects of lansoprazole in some people. Contact your doctor if you experience diarrhea or other intestinal problems. You may need a dose adjustment if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
amoxicillin clarithromycin
Applies to: Prevpac (amoxicillin / clarithromycin / lansoprazole), Prevpac (amoxicillin / clarithromycin / lansoprazole)
Information for this minor interaction is available on the professional version.
Drug and food interactions
rifAMPin food
Applies to: rifampin
Food can decrease the levels of rifAMPin in your body. Taking rifAMPin on an empty stomach (at least 30 minutes before or 2 hours after a meal) will make it easier for your body to absorb the medication. Avoid drinking alcohol while taking rifAMPin because alcohol use may increase the risk of damage to your liver. It is important to seek immediate medical care if you experience any severe side effects or symptoms of liver damage such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
clarithromycin food
Applies to: Prevpac (amoxicillin / clarithromycin / lansoprazole)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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