Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- milrinone
- Urografin 325 (diatrizoate)
Interactions between your drugs
milrinone diatrizoate
Applies to: milrinone, Urografin 325 (diatrizoate)
MONITOR: Addition of an inotropic agent to ionic radiocontrast media may produce a paradoxical depressant response that can be deleterious to the ischemic myocardium. The exact mechanism of interaction is unknown, although ionic radiocontrast agents are known to have a direct depressant effect on cardiac muscles.
MANAGEMENT: Clinicians should be aware of this potential interaction when an inotropic agent is used in combination with ionic radiocontrast media. Patients should be monitored closely for adverse cardiac effects.
References (1)
- (2007) "Product Information. Hypaque (diatrizoate)." Amersham Health
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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