Drug Interaction Report

Talk to your doctor before using medroxyPROGESTERone together with griseofulvin. Combining these medications may decrease the blood levels and effects of medroxyPROGESTERone. If you are using low-dose oral contraceptives, you may have an increased risk of breakthrough bleeding and unintended pregnancy. Because use of griseofulvin has been associated with birth defects, it is particularly important that you do not become pregnant during treatment. You should discuss the use of alternative or additional methods of birth control with your healthcare provider. Your doctor may also be able to prescribe alternatives that do not interact. If you take hormone replacement for menopause, notify your doctor if your medication is no longer controlling your symptoms or you experience abnormal bleeding. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

You may be advised to take griseofulvin with a fatty meal to increase its absorption into your body. This will make it easier for your body to absorb the medication. The combination of alcohol and griseofulvin may cause flushing and a fast heart rate. Use alcohol cautiously during treatment with griseofulvin.