Drug Interaction Report
5 potential interactions and/or warnings found for the following 2 drugs:
- itraconazole
- Voquezna Triple Pak (amoxicillin / clarithromycin / vonoprazan)
Interactions between your drugs
clarithromycin itraconazole
Applies to: Voquezna Triple Pak (amoxicillin / clarithromycin / vonoprazan), itraconazole
Using itraconazole together with clarithromycin may increase the effects of itraconazole. Contact your doctor if you experience dizziness, ringing in the ears, headache, nausea, vomiting, diarrhea, and abdominal pain. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
itraconazole vonoprazan
Applies to: itraconazole, Voquezna Triple Pak (amoxicillin / clarithromycin / vonoprazan)
Talk to your doctor before using itraconazole together with vonoprazan. Combining these medications may interfere with the absorption of itraconazole and reduce its effectiveness. Your doctor may be able to prescribe alternative medications that do not interact, or you may need a dose adjustment to safely use both medications. Taking itraconazole with a cola beverage may also help by increasing stomach acid. Contact your doctor if your infection does not improve or gets worse. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
amoxicillin clarithromycin
Applies to: Voquezna Triple Pak (amoxicillin / clarithromycin / vonoprazan), Voquezna Triple Pak (amoxicillin / clarithromycin / vonoprazan)
Information for this minor interaction is available on the professional version.
Drug and food interactions
itraconazole food
Applies to: itraconazole
Food increases the absorption of itraconazole capsules but decreases the absorption of itraconazole oral solution. Capsules should be taken immediately after a full meal and the solution be taken on an empty stomach to ensure best results.
clarithromycin food
Applies to: Voquezna Triple Pak (amoxicillin / clarithromycin / vonoprazan)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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