OTC Water Pills
Now is the time you may be finally ready to take your New Year's Resolution of weight loss a bit more seriously. While exploring different things to do to shed a few pounds, a friend suggests taking an over-the-counter water pill. Is this an actual option, though?
What is available?
In nearly every pharmacy, you will most likely find the water pill Diurex with ease. It can also be found in grocery stores and even ordered online through Amazon. Diurex contains pamabrom as its main ingredient, which can increase urination and relieve your body of water, in a similar way to drinking a caffeinated product such as coffee or black tea.
What are water pills taken for?
Over-the-counter (OTC) water pills, such as Diurex, are meant to help relieve discomfort caused by bloating, temporary water weight gain, swelling, and full feelings related to premenstrual or menstrual periods. After one dose, you'll have the urge to release any additional water your body is holding onto as the pill encourages urination, helping to relieve symptoms such as feeling heavy or weighed down.
What does my pharmacist want me to know about OTC water pills?
Water pills should be taken with a full glass of water and can be repeated after six hours if necessary. If your urine appears temporarily darker than usual or more of a golden color, this is normal and should not cause concern. It is important to understand, though, that OTC water pills are only intended to relieve bloating symptoms associated with premenstrual and/or menstrual cycles and are not meant to aid in permanent weight loss.
Related questions
- Can you take tramadol with acetaminophen, ibuprofen, or aspirin?
- What's the best medicine for sore throat?
- Acetaminophen vs paracetamol: What do you need to know?
What safety concerns should I have?
To avoid dehydration and electrolyte imbalances, it's important to drink adequate amounts of water (between six and eight glasses) throughout the day. If bloating symptoms remain for over 10 days straight, or any new symptoms come about, consider contacting your primary provider.
Who should not use water pills (diuretics)?
In general, Diurex is a safe option for treating bloating. Some water pills may also contain additional ingredients such as acetaminophen (Tylenol) or caffeine, so it's important to be mindful of what is listed as an ingredient to avoid accidentally doubling up on medication.
Summary
Remember, Diurex is a great short-term option for bloating and other discomforts associated with your menstrual cycle. It is not, however, a reliable or safe option for permanent weight loss. Consider adding frequent exercise and a well-balanced diet to your routine to achieve a healthier lifestyle or speak with your primary provider for other methods to aid in your weight loss journey.
See also:
Related medical questions
- What medications cause liver enzymes to be elevated?
- What temperature is considered a fever?
- Is it safe to take acetaminophen every day?
- What cold medicine can you take with diabetes?
- How long does Percocet stay in your system?
- Does Mucinex help with Covid?
- Is Tylenol (acetaminophen) a blood thinner?
- Which painkiller should you use?
- Is acetaminophen (Tylenol) an NSAID Drug?
- Can I take Tylenol while pregnant?
- Cold, flu, hay fever, or COVID - Which one do I have?
- Can you Double up on Pain Medications? Safe Painkiller Combinations
- How long does it take for Tylenol to start working?
- Is acetaminophen the same as Tylenol?
- Can you take paracetamol (acetaminophen) with antibiotics?
- Can I give my dog or cat Tylenol (acetaminophen)?
- What do I need to know about Drug Interactions?
- Is Tylenol (acetaminophen) an anti-inflammatory drug?
- Over the Counter Medication for Pets
- How do I treat back pain without using opioids?
- How Can I Treat Muscle Strain or Pain?
- What antibiotics are used to treat bronchitis?
- How do I treat a mild case of COVID-19 at home?
- What Vaccines do I need if I'm over 50?
Related support groups
- Acetaminophen (163 questions, 218 members)
- Tylenol (211 questions, 232 members)
- Caffeine (47 questions, 76 members)
- Peri-DS (92 questions, 323 members)
- Electrolyte (4 questions, 14 members)
- Diurex (1 questions, 3 members)
- Pamabrom (1 questions, 6 members)
- Weight Loss (Obesity/Overweight) (861 questions, 1,512 members)
- Down Syndrome (27 questions, 22 members)
- Dehydration (11 questions, 21 members)
- Vertigo (160 questions, 419 members)

AHFS® Patient Medication Information is used with permission. ©2025, the American Society of Health-System Pharmacists, Inc. (ASHP). The ASHP Data is a part of the AHFS Drug Information®️; ASHP is not responsible for the accuracy of transpositions from the original context.