Can you take paracetamol (acetaminophen) with antibiotics?
Medically reviewed by Drugs.com. Last updated on March 31, 2025.
There are literally hundreds of antibiotics used to treat infections, so once you receive your prescription, ask your doctor or pharmacist if you can also take paracetamol (acetaminophen) at the same time that you take the antibiotic.
The best way to determine if you can take any two medications together is to have a drug interaction screen performed by a health care provider.
For example, antibiotics that may affect your liver could interact with paracetamol (acetaminophen), which can also be toxic to the liver in excessive doses or when combined with alcohol.
Usually this is not a problem, but you should always check.
See also: Drug Interaction Checker
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