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Common or street names: Coca, Coke, C, Crack, Blow, Rock, Snow, Flake, Soda Cot; the base form is called freebase or "crack"

What is cocaine?

Cocaine (C17H21NO4) is a powerfully addictive, psychoactive, stimulant drug. On the street it is usually sold as a fine, white crystal powder. The powdered, hydrochloride salt form can be snorted or dissolved in water and injected. Use in any form is illegal in the U.S. when used as recreational drug.

Freebase is cocaine hydrochloride that is processed to remove the hydrochloride salt. This ‘freebase’ form is not water-soluble; the powder can be heated and its vapors smoked due to the lower melting point. Diethyl ether is used to process freebase and is highly flammable and volatile, often leading to lab explosions and bodily injury such as burns. It produces a much more intense "rush" than snorting the drug and can be extremely addictive due to the quick high and repeated use.

Crack cocaine ("crack") is another form that is processed into a rock form using baking soda and may contain a high percentage of impurities. The term "crack" refers to the crackling sound heard when it is heated prior to smoking. Crack abuse in the U.S. rose in the mid-1980's and is considered the most addictive form of the drug. Crack looks like small, irregularly shaped chunks (or “rocks”) of a whitish solid.

People who use cocaine in any form may "binge" -- taking the drug repeatedly within a short time and at increasingly higher doses -- to maintain their high.

Learn More: Commonly Abused Drugs and Substances

Where does cocaine come from?

Cocaine originates from coca leaves, and has been used for centuries in a variety of cultural applications. The pure drug is extracted from the Erythroxylon coca bush, found primarily in the South American countries of Peru, Bolivia, and Colombia. Coca-leaf infusions or teas have been used to combat altitude sickness and boost energy in many native tribes of South America.

The early use was not just limited to South American countries. In the U.S., it was found as an active ingredient in many elixirs and tonics used in the early 1900's and was even found in Coca-Cola products at that time.

Is cocaine dangerous?

Yes, illicit cocaine use can be extremely dangerous and deadly. The immediate physical effects of cocaine use include constricted blood vessels, dilated pupils, nausea, restlessness and increased body temperature, heart rate, and blood pressure.

Health complications of cocaine include:

The various means of using this illicit drug can produce different adverse reactions:

People who use illicit drugs, especially when injected, are at increased risk for diseases like HIV, hepatitis C, skin infections and vein collapse. Impairment of judgement can lead to risky behavior, as well. NIDA has found that use of cocaine can speed up HIV infection because the drug impairs immune function and promotes replication of the virus.

Long-term, cocaine use can lead to an increased risk for becoming malnourished due to loss of appetite. The occurrence of Parkinson's disease has been reported as well.

Is cocaine addictive?

Yes, cocaine is a strongly addictive illicit drug. Long-term effects of use can lead to tolerance, high doses and the need for more frequent use to attain the same level of pleasure during the initial period of use.

The use of cocaine increases the neurotransmitter dopamine in the brain. This sends an amplified "reward" signal to the brain, resulting in the euphoria described by users. Cocaine prevents dopamine from being recycled in the cell, and large amounts accumulate. This reinforces the drug-taking behavior and lowers sensitivity to the drug. People then take larger and more frequent doses to attain the same high and feel relief from the "crash" or withdrawal. Withdrawal symptoms can include:

Eventually, a tolerance to the high develops. Many addicts report that they seek but fail to achieve as much pleasure as they did from their first exposure. Some users will increase their dose to intensify and prolong the euphoric effects. While tolerance to the high can occur, users can also become more sensitive to the anesthetic and convulsant effects without increasing the dose taken. This increased sensitivity may explain some deaths occurring after apparently low doses.

Use in a binge, during which the drug is taken repeatedly and at increasingly high doses, may lead to a state of increasing irritability, restlessness, and paranoia. This can result in a period of paranoid psychosis, in which the user loses touch with reality and experiences auditory (hearing) hallucinations.

Because it has a tendency to decrease appetite, many chronic users can become malnourished. If used in a binge fashion, with frequent, repeated use over a short period of time, panic and paranoia may set in, with psychosis and auditory hallucinations possible.

Can I overdose on cocaine?

Yes, cocaine abuse can lead to an overdose and serious or deadly side effects after your first use or anytime thereafter. There is no specific medication that can reverse a cocaine overdose.

Cocaine use or overdose can lead to:

Is there a drug interaction between alcohol and cocaine?

A particularly concerning and common drug interaction between alcohol and cocaine has been reported.

Because cocaine often leads to a heart attack or stroke, first-responders or emergency personnel try to supply oxygen-rich blood to the affected organs. Seizure medicines may be given to help stop a seizure.

How is cocaine used medically?

In the U.S., prescription cocaine is classified as a Schedule II controlled substance, meaning it has a high potential for abuse but can be administered by a physician for legitimate medical uses. Brands names for FDA-approved topical nasal cocaine solution products include:

Cocaine is available in the U.S. as a prescription solution for local mucosal anesthesia, and for some eye, ear, and throat surgeries, but is rarely used because of safer alternatives have been developed.

A nasal solution is used for the induction of local anesthesia of the mucous membranes when performing diagnostic procedures and surgeries on or through the nasal cavities in adults. Topical cocaine may be administered by using cotton applicators or packs, installed into a cavity, or as a spray. Topical cocaine may also be applied to reduce bleeding of the mucous membranes.

How do people abuse cocaine?

Cocaine is most commonly abused by:

Cocaine hydrochloride (HCL) is water soluble due to the HCL salt and can be injected; it is also snorted in powder form. Mixing cocaine with heroin and injecting is called a "speedball" and can be especially lethal.

When purchased on the street, is usually ‘cut’ with adulterants such as cornstarch, baking soda, talcum powder, flour, lactose sugar, or other local anesthetics such as lidocaine or benzocaine. This increases the weight and allows the seller to make more profit on the street.

Other more dangerous adulterants, such as the stimulant amphetamine or synthetic opioids, including fentanyl, may also be used to cut the drug. Cutting cocaine with other illicit drugs can be especially harmful as the user is not aware of the added drug and an accidental overdose or death can occur.

Most often the powder is snorted, and the drug is laid out on a mirror, plate or other flat surface, separated into ‘lines’ and snorted nasally through a straw, rolled-up dollar bill or other inhaling device. The cocaine is absorbed into the bloodstream through the nasal tissues.

The effect, or ‘high’ with snorting may last 15 to 30 minutes, but does not occur as quickly as smoking or injecting it. Alternatively, smoking crack or injecting cocaine may have a rapid and more intense effect, but the "high" only lasts 5 to 10 minutes, often with an intense "crash", which leads to repeated use to sustain the high (an action called "binging").

How will cocaine make me feel?

The effect of cocaine is described as euphoric with increased energy, happiness, reduced fatigue, and heightened mental alertness. Users may be talkative, extraverted, and have a loss of appetite or need for sleep. They may be more sensitive to light, sounds or touch.

Some users report feelings of restlessness, irritability, and anxiety. The psychoactive and pleasurable effects are short-lived without continued administration. Continued use, or even a first-time use, can be dangerous and deadly.

Do employers test for cocaine?

Cocaine is a substance that is commonly tested for in pre-employment drug screening in the US.

In Nov. 2020, the state of Oregon voted in Measure 110 to decriminalize use of all drugs, including drugs such as cocaine. The law does not legalize the drugs - it means that the state will remove criminal penalties and prison time for possession of small amounts of illegal drugs. Instead, penalty involves a $100 fine or a “health assessment” completed at an addiction recovery center, according to Vox. The sale of drugs such as heroin or cocaine will still be illegal.

Do teens use cocaine or crack?

The extent of cocaine use in youth is important to follow to see trends and changes in drug use -- and drug choice -- over time.

In the Monitoring the Future Study: 2021 Overview Key Findings on Adolescent Drug Use, the National Institute of Drug Abuse (NIDA) found these trends in 2021 in the prevalence of cocaine use for 8th, 10th, and 12th Graders in the past year:

Compare these 2021 numbers above to 2020 use in the past year:

Overall cocaine use in these groups declined in 2021 with cocaine showing a relative decline in annual prevalence for the three grades combined of 57% (p<.001). This results in an overall annual prevalence at 0.7%, down from 1.4% in 2020.

It is interesting to compare youth numbers of cocaine use with marijuana use, the most commonly abused substance. Past-year use of marijuana / hashish in 2021:

Marijuana showed a considerable decline in 2021 of 6.7 percentage points in annual prevalence, respectively, for the three grades combined. The COVID-19 pandemic is postulated to have affected the declines in drug use overall seen among youth.

Cocaine use in pregnancy

The full extent of the effects of cocaine use on the unborn or newborn child are difficult to predict. Multiple factors can play into this outcome, such as use of other illegal drugs, maternal sexually-transmitted diseases, extent of prenatal care, and socioeconomic factors, among others.

In the mother, cocaine use can lead to a serious high blood pressure and spontaneous miscarriage. Pregnant women who abuse this drug may have other addictive habits, such as nicotine and alcohol use. Pregnant women with substance abuse and addiction should receive immediate medical and psychological healthcare to minimize these adverse outcomes.

Studies have shown that infants born to women who use cocaine during pregnancy may be delivered prematurely, have low birth rates, may have smaller head circumference, and be shorter in length.

Longer-term research is finding that exposure in utero and environmental factors may also lead to deficits in cognitive abilities, information processing, memory, and ability to complete tasks in childhood. More research is needed to understand the childhood long-term effects of exposure in pregnancy.

How is cocaine addiction treated?

The extensive abuse of cocaine has lead to efforts to develop treatment programs for this type of drug abuse. The majority of abusers seeking treatment programs smoke crack, and are likely to abuse multiple drugs. Many people may need to stay in rehabilitation (rehab) center during treatment. Sessions with a therapist can help you to have successful treatment.

As of 2022, there are no FDA-approved medications to treat cocaine addiction. However, research is ongoing. One of the National Institute on Drug Abuse's (NIDA) top research priorities is to find a medication to block or greatly reduce its effects, to be used as one part of a comprehensive treatment program. Research is focusing on dopamine, serotonin, gamma-aminobutyric acid (GABA), glutamate, and norepinephrine neurotransmitters involved in chemical messaging in the brain.

Several medications have been investigated for their safe use in treating cocaine addiction.

Providing the optimal combination of treatment and services for each individual is critical to successful outcomes. Ultimately, a combination of both treatments may be the most effective option.

Who should I contact for help?

Call SAMHSA’s National Helpline: 1-800-662-HELP (4357). For TTY, call 1-800-487-4889. This service is confidential, free, and open 24 hours-a-day, 365-days-a-year. Available in English and Spanish.


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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.