Temaril and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Temaril (trimeprazine).
trimeprazine Alcohol (Ethanol)
Moderate Drug Interaction
GENERALLY AVOID: Concurrent use of ethanol and phenothiazines may result in additive CNS depression and psychomotor impairment. Also, ethanol may precipitate dystonic reactions in patients who are taking phenothiazines. The two drugs probably act on different sites in the brain, although the exact mechanism of the interaction is not known.
MANAGEMENT: Patients should be advised to avoid alcohol during phenothiazine therapy.
References
- Lutz EG (1976) "Neuroleptic-induced akathisia and dystonia triggered by alcohol." JAMA, 236, p. 2422-3
- Freed E (1981) "Alcohol-triggered-neuroleptic-induced tremor, rigidity and dystonia." Med J Aust, 2, p. 44-5
Temaril drug interactions
There are 684 drug interactions with Temaril (trimeprazine).
Temaril disease interactions
There are 17 disease interactions with Temaril (trimeprazine) which include:
- acute alcohol intoxication
- cardiovascular disease
- CNS depression
- head injury
- anticholinergic effects
- asthma/COPD
- anticholinergic effects
- breast cancer
- dystonic reactions
- hematologic toxicity
- liver disease
- NMS
- parkinsonism
- renal dysfunction
- respiratory disorders
- seizure disorders
- tardive dyskinesia
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.