Orapred ODT and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with Orapred ODT (prednisolone).
High Blood Pressure (Hypertension)
Moderate Potential Hazard, Moderate plausibility
corticosteroids - fluid retention
Corticosteroids may cause hypernatremia, hypokalemia, fluid retention, and elevation in blood pressure. Large doses of any corticosteroid can demonstrate these effects, particularly if given for longer periods. Therapy with corticosteroids should be administered cautiously in patients with preexisting fluid retention, hypertension, congestive heart failure, and/or renal dysfunction. Dietary sodium restriction and potassium supplementation may be advisable.
References
- "Product Information. Hydeltrasol (prednisolone)." Merck & Co., Inc PROD (2001):
- "Product Information. Deltasone (prednisone)." Pharmacia and Upjohn PROD (2001):
- "Product Information. Decadron (dexamethasone)." Merck & Co., Inc PROD (2001):
- "Product Information. Hydrocortone (hydrocortisone)." Merck & Co., Inc PROD (2001):
- "Product Information. Medrol (methylprednisolone)." Pharmacia and Upjohn PROD (2001):
- "Product Information. Florinef Acetate (fludrocortisone)." Bristol-Myers Squibb PROD (2001):
- "Product Information. Cortone Acetate (cortisone)." Merck & Co., Inc PROD (2001):
- "Product Information. Kenalog (triamcinolone)." Bristol-Myers Squibb PROD (2001):
- "Product Information. Celestone (betamethasone)." Schering Corporation PROD (2001):
- "Product Information. Emflaza (deflazacort)." PTC Therapeutics, Inc. SUPPL-5 (2021):
- "Product Information. Agamree (vamorolone)." Santhera Pharmaceuticals (US) (2023):
High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)
Moderate Potential Hazard, Moderate plausibility
corticosteroids - hyperlipidemia
Corticosteroids may elevate serum triglyceride and LDL cholesterol levels if used for longer than brief periods. Patients with preexisting hyperlipidemia may require closer monitoring during prolonged corticosteroid therapy, and adjustments made accordingly in their lipid-lowering regimen.
References
- Seale JP, Compton MR "Side-effects of corticosteroid agents." Med J Aust 144 (1986): 139-42
- "Product Information. Hydeltrasol (prednisolone)." Merck & Co., Inc PROD (2001):
- "Product Information. Deltasone (prednisone)." Pharmacia and Upjohn PROD (2001):
- "Product Information. Decadron (dexamethasone)." Merck & Co., Inc PROD (2001):
- "Product Information. Hydrocortone (hydrocortisone)." Merck & Co., Inc PROD (2001):
- "Product Information. Medrol (methylprednisolone)." Pharmacia and Upjohn PROD (2001):
- "Product Information. Florinef Acetate (fludrocortisone)." Bristol-Myers Squibb PROD (2001):
- "Product Information. Cortone Acetate (cortisone)." Merck & Co., Inc PROD (2001):
- "Product Information. Kenalog (triamcinolone)." Bristol-Myers Squibb PROD (2001):
- "Product Information. Celestone (betamethasone)." Schering Corporation PROD (2001):
Orapred ODT drug interactions
There are 589 drug interactions with Orapred ODT (prednisolone).
Orapred ODT disease interactions
There are 23 disease interactions with Orapred ODT (prednisolone) which include:
- infections
- prematurity
- (+) tuberculin test
- cirrhosis
- depression/psychoses
- diabetes
- electrolyte imbalance
- fluid retention
- GI perforation
- hyperadrenocorticalism
- hyperlipidemia
- hypothyroidism
- liver disease
- MI
- myasthenia gravis
- myopathy
- ocular herpes simplex
- ocular toxicities
- osteoporosis
- PUD
- scleroderma
- strongyloidiasis
- thromboembolism
More about Orapred ODT (prednisolone)
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- During pregnancy
- FDA approval history
- Drug class: glucocorticoids
- Breastfeeding
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Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.