Oxytetracycline / phenazopyridine / sulfamethizole and Alcohol / Food Interactions
There are 2 alcohol/food/lifestyle interactions with oxytetracycline / phenazopyridine / sulfamethizole which include:
oxytetracycline ↔ multivitamins with minerals
Moderate Drug Interaction
Iron can bind to oxytetracycline in the gastrointestinal tract, which may prevent their absorption into the bloodstream and possibly reduce their effectiveness. To avoid or minimize the interaction, iron-containing medications and oxytetracycline should preferably be taken at least three hours apart in most cases. Talk to your doctor if you have any questions or concerns, or if you have trouble separating the dosing times. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
oxytetracycline ↔ food
Moderate Food Interaction
Consumer information for this interaction is not currently available.
ADJUST DOSING INTERVAL: Administration with food, particularly dairy products, significantly reduces tetracycline absorption. The calcium content of these foods forms nonabsorbable chelates with tetracycline.
MANAGEMENT: Tetracycline should be administered one hour before or two hours after meals.
References
- "Product Information. Achromycin (tetracycline)." Lederle Laboratories, Wayne, NJ.
- "Product Information. Declomycin (demeclocycline)." Lederle Laboratories, Wayne, NJ.
oxytetracycline / phenazopyridine / sulfamethizole drug Interactions
There are 379 drug interactions with oxytetracycline / phenazopyridine / sulfamethizole
oxytetracycline / phenazopyridine / sulfamethizole disease Interactions
There are 9 disease interactions with oxytetracycline / phenazopyridine / sulfamethizole which include:
- G-6-Pd Deficiency
- Hepatitis
- Renal Dysfunction
- Hematologic Toxicity
- Colitis
- Hemodialysis
- Hepatotoxicity
- Renal Dysfunction
- Esophageal Irritation
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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