Glecaprevir/pibrentasvir and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with glecaprevir / pibrentasvir.
Glecaprevir Food/Lifestyle
Moderate Food Interaction
ADJUST DOSING INTERVAL: Food enhances the oral bioavailability of glecaprevir and pibrentasvir. Relative to fasting conditions, mean glecaprevir systemic exposure (AUC) increased by 83% to 163% and mean pibrentasvir AUC increased by 40% to 53% when administered with moderate to high fat meals.
MANAGEMENT: Glecaprevir-pibrentasvir should be administered with food.
References (1)
- (2017) "Product Information. Mavyret (glecaprevir-pibrentasvir)." Abbott Pharmaceutical
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Glecaprevir/pibrentasvir drug interactions
There are 217 drug interactions with glecaprevir / pibrentasvir.
Glecaprevir/pibrentasvir disease interactions
There are 2 disease interactions with glecaprevir / pibrentasvir which include:
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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