Glecaprevir/pibrentasvir and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with glecaprevir / pibrentasvir.
Glecaprevir Food
Moderate Food Interaction
Consumer information for this interaction is not currently available.
ADJUST DOSING INTERVAL: Food enhances the oral bioavailability of glecaprevir and pibrentasvir. Relative to fasting conditions, mean glecaprevir systemic exposure (AUC) increased by 83% to 163% and mean pibrentasvir AUC increased by 40% to 53% when administered with moderate to high fat meals.
MANAGEMENT: Glecaprevir-pibrentasvir should be administered with food.
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Glecaprevir/pibrentasvir drug interactions
There are 215 drug interactions with glecaprevir / pibrentasvir.
Glecaprevir/pibrentasvir disease interactions
There are 2 disease interactions with glecaprevir / pibrentasvir which include:
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.