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H.P. Acthar Gel (corticotropin) and Alcohol / Food Interactions

There is 1 alcohol/food/lifestyle interaction with H.P. Acthar Gel (corticotropin):


High Blood Pressure (Hypertension)

Severe Potential Hazard, Moderate plausibility

ACTH - fluid retention

Adrenocorticotropic agents may cause hypernatremia, hypokalemia, fluid retention, and elevation in blood pressure. Therapy with these agents, particularly if intended for longer than brief periods, should be administered cautiously in patients with preexisting fluid retention or conditions that may be aggravated by these effects. Dietary sodium restriction and potassium supplementation may be advisable. The manufacturers consider the use of adrenocorticotropic agents to be contraindicated in patients with congestive heart failure or uncontrolled hypertension.


  1. "Product Information. Acthrel (corticorelin)." Ferring Laboratories Inc, Tarrytown, NY.
  2. "Product Information. Cortrosyn (cosyntropin)" Organon, West Orange, NJ.
  3. "Product Information. Acthar (corticotropin)." Rhone-Poulenc Rorer, Collegeville, PA.

H.P. Acthar Gel (corticotropin) drug interactions

There are 489 drug interactions with H.P. Acthar Gel (corticotropin)

H.P. Acthar Gel (corticotropin) disease interactions

There are 20 disease interactions with H.P. Acthar Gel (corticotropin) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.