Chlorpheniramine/phenylephrine/phenyltoloxamine and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with chlorpheniramine / phenylephrine / phenyltoloxamine.
Chlorpheniramine Food
Moderate Food Interaction
GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol. Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
References (4)
- Warrington SJ, Ankier SI, Turner P (1986) "Evaluation of possible interactions between ethanol and trazodone or amitriptyline." Neuropsychobiology, 15, p. 31-7
- Gilman AG, eds., Nies AS, Rall TW, Taylor P (1990) "Goodman and Gilman's the Pharmacological Basis of Therapeutics." New York, NY: Pergamon Press Inc.
- (2012) "Product Information. Fycompa (perampanel)." Eisai Inc
- (2015) "Product Information. Rexulti (brexpiprazole)." Otsuka American Pharmaceuticals Inc
Phenyltoloxamine Food
Moderate Food Interaction
GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol. Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
References (4)
- Warrington SJ, Ankier SI, Turner P (1986) "Evaluation of possible interactions between ethanol and trazodone or amitriptyline." Neuropsychobiology, 15, p. 31-7
- Gilman AG, eds., Nies AS, Rall TW, Taylor P (1990) "Goodman and Gilman's the Pharmacological Basis of Therapeutics." New York, NY: Pergamon Press Inc.
- (2012) "Product Information. Fycompa (perampanel)." Eisai Inc
- (2015) "Product Information. Rexulti (brexpiprazole)." Otsuka American Pharmaceuticals Inc
Switch to consumer interaction data
Chlorpheniramine/phenylephrine/phenyltoloxamine drug interactions
There are 495 drug interactions with chlorpheniramine / phenylephrine / phenyltoloxamine.
Chlorpheniramine/phenylephrine/phenyltoloxamine disease interactions
There are 8 disease interactions with chlorpheniramine / phenylephrine / phenyltoloxamine which include:
- cardiovascular disease
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- BPH
- diabetes
- glaucoma
Report options
More about chlorpheniramine / phenylephrine / phenyltoloxamine
- chlorpheniramine/phenylephrine/phenyltoloxamine consumer information
- Check interactions
- Compare alternatives
- Imprints, shape & color data
- Side effects
- Drug class: upper respiratory combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Benadryl
Benadryl is an antihistamine and is used to treat sneezing, runny nose, itching and other ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Promethazine DM
Promethazine DM is used for allergic rhinitis, cold symptoms, cough
Doxylamine
Doxylamine systemic is used for allergic rhinitis, allergies, conjunctivitis, allergic, insomnia ...
Mometasone nasal
Mometasone nasal is used for allergic rhinitis, allergies, nasal polyps, sinus symptoms
Sodium chloride nasal
Sodium chloride nasal is used for nasal congestion
Chlorpheniramine
Chlorpheniramine systemic is used for allergic reactions, allergic rhinitis, allergies, cold ...
Pseudoephedrine
Pseudoephedrine is used to treat nasal and sinus congestion, or congestion of the tubes that drain ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.