Ortikos and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Ortikos (budesonide).
Budesonide Food
Moderate Food Interaction
GENERALLY AVOID: Grapefruit juice may increase the plasma concentrations and systemic effects of orally administered budesonide. The proposed mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall by certain compounds present in grapefruits. According to the manufacturer, the systemic exposure of oral budesonide approximately doubles after extensive intake of grapefruit juice.
MANAGEMENT: Patients receiving budesonide should avoid the regular consumption of grapefruits and grapefruit juice to prevent undue increases in plasma budesonide levels and systemic effects.
References (1)
- (2001) "Product Information. Entocort (budesonide)." AstraZeneca Pharma Inc
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Ortikos drug interactions
There are 565 drug interactions with Ortikos (budesonide).
Ortikos disease interactions
There are 7 disease interactions with Ortikos (budesonide) which include:
- hepatic impairment
- infections
- lactose intolerance
- ocular herpes simplex
- ocular toxicities
- osteoporosis
- hyperadrenocorticism
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More about Ortikos (budesonide)
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- Drug class: glucocorticoids
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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