Victrelis and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Victrelis (boceprevir).
boceprevir food
Moderate Food Interaction
ADJUST DOSING INTERVAL: Food significantly enhances the oral bioavailability of boceprevir. When given at 800 mg three times daily with food, boceprevir exposure increased by up to 65% relative to administration in the fasting state. The bioavailability of boceprevir was similar regardless of meal type (e.g., high-fat versus low-fat) or whether taken 5 minutes prior to eating, during a meal, or immediately following completion of the meal. Therefore, boceprevir may be taken without regard to either meal type or timing of the meal.
MANAGEMENT: To ensure maximal oral absorption, boceprevir should be administered with a meal or light snack.
References
- "Product Information. Victrelis (boceprevir)." Schering-Plough Corporation (2011):
Victrelis drug interactions
There are 452 drug interactions with Victrelis (boceprevir).
Victrelis disease interactions
There is 1 disease interaction with Victrelis (boceprevir) which include:
More about Victrelis (boceprevir)
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- Drug class: protease inhibitors
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
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