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Victrelis (boceprevir) Disease Interactions

There is 1 disease interaction with Victrelis (boceprevir):

Moderate

Boceprevir (Includes Victrelis) ↔ Pancytopenia

Moderate Potential Hazard, Moderate plausibility

Applies to: Anemia, Pancytopenia, Neutropenia, Thrombocytopenia

Anemia, neutropenia and thrombocytopenia has been reported with the use of boceprevir. Boceprevir is always administered with peginterferon alfa and ribavirin which are also associated with pancytopenia. The addition of boceprevir has shown an additional decrease in hemoglobin and blood cell counts. Caution should be used in patients with preexisting anemia, neutropenia or thrombocytopenia. A complete blood count should be obtained pretreatment, and then during treatment at weeks 2, 4, 8, and 12. Patients should be monitored closely. Refer to the prescribing information for peginterferon alfa and ribavirin for additional information regarding dose reduction or discontinuation based on laboratory parameters. If ribavirin and peginterferon alfa need to be discontinued, boceprevir should be discontinued as well.

Victrelis (boceprevir) drug Interactions

There are 486 drug interactions with Victrelis (boceprevir)

Victrelis (boceprevir) alcohol/food Interactions

There is 1 alcohol/food interaction with Victrelis (boceprevir)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.

Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.

Do not stop taking any medications without consulting your healthcare provider.

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