Bevyxxa and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Bevyxxa (betrixaban).
Betrixaban Food/Lifestyle
Moderate Food Interaction
ADJUST DOSING INTERVAL: Food reduces the oral bioavailability of betrixaban. When administered with a low-fat (900 calories; 20% fat) or high-fat (900 calories; 60% fat) meal, betrixaban peak plasma concentration (Cmax) and systemic exposure (AUC) decreased relative to administration in the fasting state by an average of 70% and 61%, respectively, with the low-fat meal and 50% and 48%, respectively, with the high-fat meal. The effect of food on betrixaban pharmacokinetics could be observed for up to 6 hours after meal intake.
MANAGEMENT: The manufacturer recommends taking betrixaban at the same time each day with food.
References (1)
- (2017) "Product Information. Bevyxxa (betrixaban)." Portola Pharmaceuticals
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Bevyxxa drug interactions
There are 294 drug interactions with Bevyxxa (betrixaban).
Bevyxxa disease interactions
There are 4 disease interactions with Bevyxxa (betrixaban) which include:
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More about Bevyxxa (betrixaban)
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- Drug class: factor Xa inhibitors
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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