Bevyxxa and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Bevyxxa (betrixaban).
betrixaban food
Moderate Food Interaction
ADJUST DOSING INTERVAL: Food reduces the oral bioavailability of betrixaban. When administered with a low-fat (900 calories; 20% fat) or high-fat (900 calories; 60% fat) meal, betrixaban peak plasma concentration (Cmax) and systemic exposure (AUC) decreased relative to administration in the fasting state by an average of 70% and 61%, respectively, with the low-fat meal and 50% and 48%, respectively, with the high-fat meal. The effect of food on betrixaban pharmacokinetics could be observed for up to 6 hours after meal intake.
MANAGEMENT: The manufacturer recommends taking betrixaban at the same time each day with food.
References
- "Product Information. Bevyxxa (betrixaban)." Portola Pharmaceuticals (2017):
Bevyxxa drug interactions
There are 277 drug interactions with Bevyxxa (betrixaban).
Bevyxxa disease interactions
There are 4 disease interactions with Bevyxxa (betrixaban) which include:
Report options
More about Bevyxxa (betrixaban)
- Bevyxxa consumer information
- Check interactions
- Compare alternatives
- Imprints, shape & color data
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: factor Xa inhibitors
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.