Bevyxxa Dosage

Recommended Dose

The recommended dose of BEVYXXA is an initial single dose of 160 mg, followed by 80 mg once daily. Daily oral doses should be given at the same time of day with food.

The recommended duration of treatment is 35 to 42 days.

Use with P-gp Inhibitors

For patients receiving or starting concomitant P-gp inhibitors the recommended dose of BEVYXXA is an initial single dose of 80 mg followed by 40 mg once daily. The recommended duration of treatment is 35 to 42 days.

Patients with Severe Renal Impairment

For patients with severe renal impairment (CrCl ≥ 15 to < 30 mL/min computed by Cockcroft-Gault using actual body weight) the recommended dose of BEVYXXA is an initial single dose of 80 mg followed by 40 mg once daily. The recommended duration of treatment is 35 to 42 days.

Patients with Hepatic Impairment

Avoid use of BEVYXXA in patients with moderate or severe hepatic impairment. No dose adjustment is required in patients with mild hepatic impairment.

Missed Dose

If a dose of BEVYXXA is not taken at the scheduled time, the dose should be taken as soon as possible on the same day. The BEVYXXA dose should not be doubled to make up for a missed dose.