Fosamax Plus D (alendronate / cholecalciferol) and Alcohol / Food Interactions
There are 3 alcohol/food/lifestyle interactions with Fosamax Plus D (alendronate / cholecalciferol) which include:
multivitamins with minerals ↔ alendronate
Moderate Drug Interaction
Alendronate and multivitamin with minerals should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of alendronate and reduce its effectiveness. You should take multivitamin with minerals at least 30 minutes after the alendronate dose. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
alendronate ↔ food
Moderate Food Interaction
Consumer information for this interaction is not currently available.
ADJUST DOSING INTERVAL: Food significantly decreases the bioavailability of alendronate, possibly to negligible levels.
MANAGEMENT: Alendronate should be administered with 6 to 8 ounces of plain water, at least 30 minutes before the first food, beverage, or medication of the day. Patients should remain upright for at least 30 minutes following administration of alendronate.
- "Product Information. Fosamax (alendronate)." Merck & Co, Inc, West Point, PA.
High Blood Pressure (Hypertension)
Moderate Potential Hazard, Moderate plausibility
alendronate - CV
Each tablet of Binosto (alendronate effervescent) contains 650 mg sodium, equivalent to 1650 mg NaCl. Use caution in patients on sodium restriction, such as patients with a history of heart failure, hypertension, or other cardiovascular diseases.
Fosamax Plus D (alendronate / cholecalciferol) drug Interactions
There are 328 drug interactions with Fosamax Plus D (alendronate / cholecalciferol)
Fosamax Plus D (alendronate / cholecalciferol) disease Interactions
There are 12 disease interactions with Fosamax Plus D (alendronate / cholecalciferol) which include:
- Upper Gi Mucosal Irritation
- Electrolyte Imbalance
- Renal Dysfunction
- Renal Dysfunction
- Hepatobiliary Dysfunction
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
|Major||Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderate||Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minor||Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
Do not stop taking any medications without consulting your healthcare provider.
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