Talacen (acetaminophen / pentazocine) and Alcohol / Food Interactions
There are 2 alcohol/food/lifestyle interactions with Talacen (acetaminophen / pentazocine) which include:
acetaminophen ↔ Alcohol (Ethanol)
Major Drug Interaction
Ask your doctor before using acetaminophen together with ethanol. This can cause serious side effects that affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
pentazocine ↔ Alcohol (Ethanol)
Moderate Drug Interaction
Do not use alcohol or medications that contain alcohol while you are receiving treatment with pentazocine. This may increase nervous system side effects such as drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment. In severe cases, low blood pressure, respiratory distress, fainting, coma, or even death may occur. With certain long-acting formulations of narcotic pain medication, consumption of alcohol may also cause rapid release of the drug, resulting in high blood levels that may be potentially lethal. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. Do not use more than the recommended dose of pentazocine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
pentazocine ↔ food
Moderate Food Interaction
Consumer information for this interaction is not currently available.
MONITOR: Smoking tobacco may decrease the plasma concentrations and effects of pentazocine by enhancing its metabolic clearance.
MANAGEMENT: The possibility of reduced therapeutic effects of pentazocine should be considered in smokers.
- Miller LG "Recent developments in the study of the effects of cigarette smoking on clinical pharmacokinetics and clinical pharmacodynamics." Clin Pharmacokinet 17 (1989): 90-108
- D'Arcy PF "Tobacco smoking and drugs: a clinically important interaction?" Drug Intell Clin Pharm 18 (1984): 302-7
- "Product Information. Talacen (acetaminophen-pentazocine)." Sanofi-Synthelabo Inc, New York, NY.
Talacen (acetaminophen / pentazocine) drug Interactions
There are 877 drug interactions with Talacen (acetaminophen / pentazocine)
Talacen (acetaminophen / pentazocine) disease Interactions
There are 17 disease interactions with Talacen (acetaminophen / pentazocine) which include:
- Liver Disease
- Impaired Gi Motility
- Infectious Diarrhea
- Liver Disease
- Renal Dysfunction
- Acute Mi
- Drug Dependence
- Intracranial Pressure
- Respiratory Depression
- Adrenal Insufficiency
- Biliary Spasm
- Seizure Disorders
- Urinary Retention
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.