Acetaminophen / pentazocine Pregnancy and Breastfeeding Warnings

Brand names: Talacen

Acetaminophen / pentazocine Pregnancy Warnings

Acetaminophen-pentazocine has been assigned to pregnancy category C by the FDA. Animal studies have not been reported with the combination of acetaminophen and pentazocine. Animal studies have revealed evidence of teratogenicity with pentazocine. There are no controlled data in human pregnancy. Frequent acetaminophen use (defined as most days or daily use) in late pregnancy may be associated with increased risk of persistent wheezing in the infant which may persist into childhood. Possible abstinence syndromes in newborns following prolonged use of pentazocine during pregnancy have been reported rarely. Acetaminophen-pentazocine is only recommended for use during pregnancy when benefit outweighs risk.

Pentazocine can cross the placental barrier and cause central nervous system depression in the neonate, and if used regularly during pregnancy, may lead to withdrawal symptoms in the newborn.

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Acetaminophen / pentazocine Breastfeeding Warnings

Acetaminophen and pentazocine are excreted into human milk. The manufacturer recommends that caution be used when administering acetaminophen-pentazocine to nursing women.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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