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Acetaminophen / pentazocine Pregnancy and Breastfeeding Warnings

Acetaminophen / pentazocine is also known as: Talacen

Acetaminophen / pentazocine Pregnancy Warnings

Pentazocine can cross the placental barrier and cause central nervous system depression in the neonate, and if used regularly during pregnancy, may lead to withdrawal symptoms in the newborn.

Acetaminophen-pentazocine has been assigned to pregnancy category C by the FDA. Animal studies have not been reported with the combination of acetaminophen and pentazocine. Animal studies have revealed evidence of teratogenicity with pentazocine. There are no controlled data in human pregnancy. Frequent acetaminophen use (defined as most days or daily use) in late pregnancy may be associated with increased risk of persistent wheezing in the infant which may persist into childhood. Possible abstinence syndromes in newborns following prolonged use of pentazocine during pregnancy have been reported rarely. Acetaminophen-pentazocine is only recommended for use during pregnancy when benefit outweighs risk.

See references

Acetaminophen / pentazocine Breastfeeding Warnings

Acetaminophen and pentazocine are excreted into human milk. The manufacturer recommends that caution be used when administering acetaminophen-pentazocine to nursing women.

See references

References for pregnancy information

  1. "Product Information. Talacen (acetaminophen-pentazocine)." Sanofi-Synthelabo Inc, New York, NY.

References for breastfeeding information

  1. "Product Information. Talacen (acetaminophen-pentazocine)." Sanofi-Synthelabo Inc, New York, NY.

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