Sulfamethoxazole Interactions
There are 382 drugs known to interact with sulfamethoxazole, along with 9 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 21 are major, 151 are moderate, and 210 are minor.
- View all 382 medications that may interact with sulfamethoxazole
- View sulfamethoxazole alcohol/food interactions (1)
- View sulfamethoxazole disease interactions (9)
Most frequently checked interactions
View interaction reports for sulfamethoxazole and the medicines listed below.
- Advair Diskus (fluticasone / salmeterol)
- Aspirin Low Strength (aspirin)
- Bactrim (sulfamethoxazole / trimethoprim)
- Benadryl (diphenhydramine)
- Celebrex (celecoxib)
- CoQ10 (ubiquinone)
- Crestor (rosuvastatin)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Mucinex (guaifenesin)
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- ProAir HFA (albuterol)
- Symbicort (budesonide / formoterol)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Tylenol Extra Strength (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Xarelto (rivaroxaban)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Sulfamethoxazole alcohol/food interactions
There is 1 alcohol/food interaction with sulfamethoxazole.
Sulfamethoxazole disease interactions
There are 9 disease interactions with sulfamethoxazole which include:
- colitis
- hematologic toxicity
- hypersensitivity reactions
- liver disease
- porphyria
- renal dysfunction
- crystalluria
- hemodialysis
- urinary obstruction
Report options
More about sulfamethoxazole
- Compare alternatives
- Reviews (2)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Support group
- Drug class: sulfonamides
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
