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Pralatrexate Drug Interactions

A total of 240 drugs are known to interact with pralatrexate.

  • 35 major drug interactions
  • 203 moderate drug interactions
  • 2 minor drug interactions

Check for interactions

Type in a drug name to check for interactions with pralatrexate.

Medications known to interact with pralatrexate

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    • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Children's Motrin, Proprinal, Motrin IB, Childrens Ibuprofen Berry, Advil Children's, Ibuprofen PMR, Ibu-8, Rufen, IBU-200, Motrin Childrens, Advil Migraine, Caldolor, Ibu-Tab, Menadol, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Pediatric, Genpril, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, Addaprin, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, Motrin Junior Strength, Motrin Infant Drops, NeoProfen, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
    • ibuprofen / oxycodone (Combunox)
    • ibuprofen / phenylephrine (Advil Congestion Relief, Advil Sinus Congestion & Pain)
    • ibuprofen / pseudoephedrine (Advil Cold and Sinus, Advil Cold and Sinus Liqui-Gels, Dristan Sinus, Motrin IB Sinus, Sine-Aid IB, Motrin Cold and Flu, Motrin Childrens Cold, Motrin Sinus Headache, Advil Children's Cold)
    • idelalisib (Zydelig)
    • indomethacin (Indocin, Indocin SR, Tivorbex, Indocin IV)
    • infliximab (Remicade, Inflectra, Renflexis, Ixifi)
    • influenza virus vaccine, h1n1, inactivated
    • influenza virus vaccine, h1n1, live
    • influenza virus vaccine, h5n1 (H5N1 Influenza Vaccine)
    • influenza virus vaccine, inactivated (Fluzone, Afluria, Fluvirin, Fluzone High-Dose, Fluad, Flucelvax, Fluarix, Flucelvax Quadrivalent, Fluzone Quadrivalent, Afluria Quadrivalent, Fluarix Quadrivalent, Flublok, FluLaval, FluLaval Quadrivalent, Flublok Quadrivalent, Fluzone Preservative-Free Quadrivalent, Fluzone Intradermal Quadrivalent, Fluzone Intradermal, Fluvirin Preservative-Free, Fluzone Preservative-Free, Fluzone Preservative-Free Pediatric, Fluzone Preservative-Free Pediatric Quadrivalent, Afluria 2017-2018, Fluad 2017-2018, Fluvirin 2017-2018, Fluvirin Preservative-Free 2017-2018, Fluzone High-Dose 2017-2018, Fluzone Preservative-Free Quadrivalent 2017-2018, Fluzone Quadrivalent 2017-2018, Fluzone Quadrivalent Intradermal 2017-2018, Flushield, Fluogen, Agriflu)
    • influenza virus vaccine, live, trivalent (FluMist, FluMist Quadrivalent)
    • interferon beta-1a (Avonex, Rebif, Avonex Pen, Avonex Prefilled Syringe, Rebif Rebidose)
    • interferon beta-1b (Betaseron, Extavia)
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    • ketoprofen (Orudis, Actron, Oruvail, Nexcede, Orudis KT)
    • ketorolac (Toradol, Sprix, Toradol IV/IM, Toradol IM)
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    • valganciclovir (Valcyte)
    • varicella virus vaccine (Varivax)
    • vitamin e (Alpha E, Aquasol E, Aqua-E, Aqua Gem-E, E-600, E-Gems, E Pherol, Amino-Opti-E, Vita-Plus E Natural, Nutr-E-Sol, E-400 Clear, Centrum Singles-Vitamin E, Aquavite-E, E-Max-1000)
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    Pralatrexate disease interactions

    There are 2 disease interactions with pralatrexate which include:

    Drug Interaction Classification

    These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
    Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
    Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
    Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
    Unknown No interaction information available.

    Further information

    Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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