Mercaptopurine Drug Interactions
Currently displaying a list of 297 drugs known to interact with mercaptopurine.
- 60 major drug interactions
- 222 moderate drug interactions
- 15 minor drug interactions
Medications known to interact with mercaptopurine
Note: Showing generic names only.
A
- abrocitinib
- adalimumab
- adenovirus vaccine
- aldesleukin
- alefacept
- alemtuzumab
- allogeneic processed thymus tissue
- allopurinol
- anakinra
- anisindione
- anthrax vaccine adsorbed
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- atezolizumab
- avelumab
- azathioprine
B
- balsalazide
- baricitinib
- bcg
- bcg vaccine
- bedaquiline
- bendamustine
- bifidobacterium infantis
- bifidobacterium longum
- black cohosh
- bleomycin
- brentuximab
- brewer's yeast
- busulfan
C
- cabazitaxel
- calaspargase pegol
- canakinumab
- candida albicans extract
- cannabidiol
- capecitabine
- carboplatin
- carmustine
- cemiplimab
- certolizumab
- chikungunya vaccine, live (cvx 317)
- chikungunya vaccine, recombinant (cvx 329)
- chlorambucil
- chloramphenicol
- chloramphenicol ophthalmic
- chloramphenicol otic
- cholera vaccine
- cholera vaccine, live
- cinoxacin
- ciprofloxacin
- cisplatin
- cladribine
- clofarabine
- clozapine
- coccidioidin skin test
- cosibelimab
- COVID-19 mRNA (Moderna) vaccine
- COVID-19 mRNA (Pfizer) vaccine
- cyclophosphamide
- cytarabine
- cytarabine liposomal
D
- dacarbazine
- daclizumab
- dactinomycin
- daunorubicin
- daunorubicin liposomal
- decitabine
- deferiprone
- delafloxacin
- dengue vaccine
- denosumab
- deucravacitinib
- dicumarol
- dimethyl fumarate
- diroximel fumarate
- docetaxel
- dostarlimab
- doxorubicin
- doxorubicin liposomal
- durvalumab
E
- efalizumab
- efavirenz
- efbemalenograstim alfa
- eflapegrastim
- elranatamab
- enoxacin
- epirubicin
- etanercept
- ethotoin
- etoposide
- etranacogene dezaparvovec
- etrasimod
F
- febuxostat
- fidanacogene elaparvovec
- filgrastim
- fingolimod
- floxuridine
- fludarabine
- fluorouracil
- fosphenytoin
G
H
- haemophilus b conjugate (hboc) vaccine
- haemophilus b conjugate (prp-omp) vaccine
- haemophilus b conjugate (prp-t) vaccine
- hepatitis a adult vaccine
- hepatitis a pediatric vaccine
- hepatitis b adult vaccine
- hepatitis b pediatric vaccine
- histoplasmin
- human papillomavirus vaccine
- hydroxyurea
I
- ibritumomab
- idarubicin
- idelalisib
- ifosfamide
- imatinib
- infliximab
- influenza virus vaccine, h1n1, inactivated
- influenza virus vaccine, h1n1, live
- influenza virus vaccine, h5n1
- influenza virus vaccine, inactivated
- influenza virus vaccine, live
- interferon alfa-2a
- interferon alfa-2b
- interferon beta-1a
- interferon beta-1b
- ipilimumab
- isatuximab
- isoniazid
J
K
L
- lactobacillus acidophilus
- lactobacillus reuteri
- lactobacillus rhamnosus
- lactobacillus rhamnosus gg
- leflunomide
- levofloxacin
- levoketoconazole
- lomefloxacin
- lomitapide
- lomustine
- loncastuximab tesirine
- lurbinectedin
- lyme disease vaccine
M
- measles virus vaccine
- mechlorethamine
- melphalan
- melphalan flufenamide
- meningococcal conjugate vaccine
- meningococcal group acwy conjugate-group b vaccine (cvx 316)
- meningococcal group B vaccine
- meningococcal polysaccharide vaccine
- mephenytoin
- mesalamine
- methotrexate
- mipomersen
- mitomycin
- mitoxantrone
- mixed respiratory vaccine
- monomethyl fumarate
- moxifloxacin
- mumps skin test antigen
- mumps virus vaccine
N
- nadofaragene firadenovec
- nalidixic acid
- naltrexone
- natalizumab
- naxitamab
- nelarabine
- niraparib
- nivolumab
- norfloxacin
O
P
- paclitaxel
- paclitaxel protein-bound
- palifermin
- pegaspargase
- pegfilgrastim
- peginterferon beta-1a
- pembrolizumab
- pemetrexed
- pentostatin
- pertussis, acellular
- pexidartinib
- phenytoin
- plague vaccine
- pneumococcal 13-valent vaccine
- pneumococcal 15-valent conjugate vaccine
- pneumococcal 20-valent conjugate vaccine
- pneumococcal 21-valent conjugate vaccine
- pneumococcal 23-polyvalent vaccine
- pneumococcal 7-valent vaccine
- poliovirus vaccine, inactivated
- poliovirus vaccine, live, trivalent
- ponesimod
R
- rabies vaccine, human diploid cell
- rabies vaccine, purified chick embryo cell
- radium 223 dichloride
- remdesivir
- retifanlimab
- ribavirin
- rifampin
- rilonacept
- ritlecitinib
- roflumilast
- ropeginterferon alfa-2b
- rotavirus vaccine
- rsv vaccine pref3, recombinant
- rsv vaccine, mrna
- rsv vaccine, pref a-pref b, recombinant
- rubella virus vaccine
- ruxolitinib
- ruxolitinib topical
S
- saccharomyces boulardii lyo
- samarium sm 153 lexidronam
- sargramostim
- sars-cov-2 (covid-19) ad26 vaccine, recombinant
- sars-cov-2 (covid-19) chadox1 vaccine, recombinant
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 308)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)
- sars-cov-2 (covid-19) nvx-cov2373 vaccine, recombinant
- sars-cov-2 (covid-19) rs-nanoparticle vaccine, recombinant
- sars-cov-2 mrna (tozinameran 5y-11y) vaccine
- sars-cov-2 mrna (tozinameran 6m-4y) vaccine
- sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine
- sars-cov-2 mrna (tozinameran) vaccine
- sars-cov-2 mrna-1273 (6m-5y) vaccine
- sars-cov-2 mrna-1273 (6y-11y) vaccine
- sars-cov-2 mrna-1273 (booster only) vaccine
- sars-cov-2 nvx-cov2373 vaccine, recomb (cvx 313)
- sars-cov-2 pres dtm (booster only) vaccine, recombinant
- siponimod
- sipuleucel-T
- skin test antigens, multiple
- smallpox and mpox vaccine
- smallpox vaccine
- sodium phosphate p32
- sparfloxacin
- staphage lysate (spl)
- streptococcus salivarius
- streptozocin
- strontium-89 chloride
- sulfasalazine
T
- tafasitamab
- talimogene laherparepvec
- talquetamab
- tbo-filgrastim
- teclistamab
- temozolomide
- teriflunomide
- tetanus toxoid
- thalidomide
- thioguanine
- thiotepa
- tick-borne encephalitis (inactivated) pediatric vaccine
- tick-borne encephalitis (inactivated) vaccine
- tislelizumab
- tofacitinib
- topotecan
- toripalimab
- trabectedin
- tremelimumab
- treosulfan
- trichophyton skin test
- trimethoprim
- trovafloxacin
- tuberculin purified protein derivative
- typhoid vaccine, inactivated
- typhoid vaccine, live
U
V
- valganciclovir
- valoctocogene roxaparvovec
- varicella virus vaccine
- vinblastine
- vinorelbine
- vitamin e
- voclosporin
W
Y
Z
Mercaptopurine alcohol/food interactions
There is 1 alcohol/food interaction with mercaptopurine.
Mercaptopurine disease interactions
There are 5 disease interactions with mercaptopurine which include:
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More about mercaptopurine
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- Drug class: antimetabolites
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
