Drug interactions between azathioprine and mercaptopurine
Interactions between your drugs
Applies to: azathioprine and mercaptopurine
Ask your doctor before using azaTHIOprine together with mercaptopurine. Using these medications together may cause mercaptopurine to be more effective. Call your doctor at once if you have easy bruising or bleeding, fever, chills, sore throat, flu symptoms, mouth sores, dark urine, severe stomach pain, jaundice (yellowing of the skin or eyes), or severe nausea, vomiting, or diarrhea. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
Applies to: mercaptopurine
You may experience reduced absorption of mercaptopurine in the presence of food. Take mercaptopurine on an empty stomach 1 hour before or 2 hours after a meal. This will make it easier for your body to absorb the medication.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
Immunity modifying agents
The recommended maximum number of medicines in the 'immunity modifying agents' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'immunity modifying agents' category:
Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.