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Drug interactions between Linzess and ranitidine

Results for the following 2 drugs:
Linzess (linaclotide)
ranitidine

Interactions between your drugs

There were no interactions found in our database between Linzess and ranitidine - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Linzess

A total of 135 drugs (1103 brand and generic names) are known to interact with Linzess.

ranitidine

A total of 321 drugs (2058 brand and generic names) are known to interact with ranitidine.

Drug and food interactions

Moderate

linaclotide food

Applies to: Linzess (linaclotide)

Taking linaclotide with food may increase gastrointestinal side effects such as diarrhea, abdominal pain, and gas. The absorption of any other oral medication you may take can be affected if you develop frequent or severe diarrhea. To reduce the risk of gastrointestinal intolerance, linaclotide should be taken on an empty stomach at least 30 minutes prior to the first meal of the day. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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