Lamictal XR Drug Interactions
Currently displaying a list of 287 drugs known to interact with Lamictal XR (lamotrigine).
- 38 major drug interactions
- 237 moderate drug interactions
- 12 minor drug interactions
Medications known to interact with Lamictal XR
Note: Showing generic names only.
- acetylcarbromal
- acrivastine
- alfentanil
- allopurinol
- alprazolam
- amitriptyline
- amobarbital
- amoxapine
- apomorphine
- apraclonidine ophthalmic
- aripiprazole
- asenapine
- atazanavir
- baclofen
- benztropine
- biperiden
- brexanolone
- brexpiprazole
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromocriptine
- brompheniramine
- buprenorphine
- buspirone
- butabarbital
- butalbital
- butorphanol
- cannabidiol
- cannabis
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- cenobamate
- cetirizine
- chlophedianol
- chloral hydrate
- chlorcyclizine
- chlordiazepoxide
- chlormezanone
- chloroquine
- chlorotrianisene
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorzoxazone
- citalopram
- clemastine
- clobazam
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- codeine
- colesevelam
- conjugated estrogens
- conjugated estrogens topical
- cyclizine
- cyclobenzaprine
- cyproheptadine
- dalfampridine
- dantrolene
- daridorexant
- dehydroepiandrosterone
- desipramine
- desmopressin
- desvenlafaxine
- deutetrabenazine
- dexbrompheniramine
- dexmedetomidine
- dextromethorphan
- dezocine
- dienestrol topical
- diethylstilbestrol
- difelikefalin
- dimenhydrinate
- diphenhydramine
- disopyramide
- divalproex sodium
- dofetilide
- doxepin
- doxylamine
- dronabinol
- droperidol
- drospirenone
- duloxetine
- entacapone
- escitalopram
- esketamine
- eslicarbazepine
- estazolam
- esterified estrogens
- estradiol
- estradiol topical
- estramustine
- estrone
- estropipate
- estropipate topical
- eszopiclone
- ethanol
- ethinyl estradiol
- etonogestrel
- evening primrose
- ezogabine
- felbamate
- fenfluramine
- fentanyl
- flavoxate
- flecainide
- flibanserin
- fluoxetine
- fluphenazine
- flurazepam
- fluvoxamine
- folic acid
- fosphenytoin
- halazepam
- haloperidol
- heroin
- hydrocodone
- hydromorphone
- hydroxychloroquine
- hydroxyprogesterone
- hydroxyzine
- l-methylfolate
- lacosamide
- lasmiditan
- lemborexant
- leucovorin
- levocetirizine
- levodopa
- levoleucovorin
- levomefolate calcium
- levomethadyl acetate
- levomilnacipran
- levonorgestrel
- levorphanol
- lidocaine
- lithium
- lofexidine
- lorazepam
- loxapine
- lumateperone
- lurasidone
- maprotiline
- medroxyprogesterone
- mefloquine
- melatonin
- meperidine
- meprobamate
- mesoridazine
- metaxalone
- metformin
- methadone
- methocarbamol
- methohexital
- methotrexate
- metoclopramide
- metyrosine
- mexiletine
- midazolam
- milnacipran
- mitotane
- molindone
- moricizine
- morphine
- morphine liposomal
- multivitamin, prenatal
- olanzapine
- oliceridine
- olopatadine nasal
- opicapone
- opium
- orlistat
- orphenadrine
- oxazepam
- oxcarbazepine
- oxycodone
- oxymorphone
- paliperidone
- paraldehyde
- paroxetine
- pemoline
- pentazocine
- pentobarbital
- perampanel
- pergolide
- perphenazine
- phenelzine
- phenobarbital
- phenytoin
- pimozide
- porfimer
- pralatrexate
- pramipexole
- pregabalin
- primidone
- procainamide
- prochlorperazine
- procyclidine
- progesterone
- progesterone topical
- proguanil
- promazine
- promethazine
- propafenone
- propiomazine
- propoxyphene
- protriptyline
- pyrilamine
- pyrimethamine
- safinamide
- scopolamine
- secobarbital
- selegiline
- sertraline
- sodium oxybate
- stiripentol
- sufentanil
- suvorexant
- tapentadol
- tasimelteon
- temazepam
- tetrabenazine
- thalidomide
- thioridazine
- thiothixene
- tizanidine
- tocainide
- tolterodine
- tramadol
- tranylcypromine
- trazodone
- triazolam
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethobenzamide
- trimethoprim
- trimetrexate
- trimipramine
- tripelennamine
- triprolidine
- valbenazine
- valerian
- valproic acid
- varenicline
- vasopressin
- venlafaxine
- vigabatrin
- vilazodone
- vortioxetine
Lamictal XR alcohol/food interactions
There is 1 alcohol/food interaction with Lamictal XR (lamotrigine).
Lamictal XR disease interactions
There are 8 disease interactions with Lamictal XR (lamotrigine) which include:
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More about Lamictal XR (lamotrigine)
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- Latest FDA alerts (6)
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- Dosage information
- During pregnancy
- Generic availability
- FDA approval history
- Drug class: triazine anticonvulsants
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
