Ibrutinib Drug Interactions
Currently displaying a list of 502 drugs known to interact with ibrutinib.
- 198 major drug interactions
- 298 moderate drug interactions
- 6 minor drug interactions
Medications known to interact with ibrutinib
Note: Showing generic names only.
A
- abciximab
- abrocitinib
- acalabrutinib
- adagrasib
- adalimumab
- adenovirus vaccine
- ado-trastuzumab emtansine
- afatinib
- alefacept
- alemtuzumab
- aliskiren
- allogeneic processed thymus tissue
- alpelisib
- alteplase
- ambrisentan
- aminoglutethimide
- amiodarone
- amobarbital
- amprenavir
- anagrelide
- anakinra
- anifrolumab
- anisindione
- anistreplase
- anthrax vaccine adsorbed
- antithrombin iii
- apalutamide
- apixaban
- aprepitant
- ardeparin
- argatroban
- armodafinil
- artesunate
- asciminib
- aspirin
- atazanavir
- atezolizumab
- avacopan
- avapritinib
- avelumab
- azathioprine
B
- baricitinib
- bcg
- bcg vaccine
- belimumab
- belzutifan
- berotralstat
- betrixaban
- bexarotene
- bifidobacterium infantis
- bifidobacterium longum
- bimekizumab
- binimetinib
- bivalirudin
- boceprevir
- bosentan
- bosutinib
- brewer's yeast
- brodalumab
- bromfenac
- bromfenac ophthalmic
- butabarbital
- butalbital
C
- cabozantinib
- canakinumab
- candida albicans extract
- cangrelor
- capivasertib
- caplacizumab
- carbamazepine
- cemiplimab
- cenobamate
- ceritinib
- certolizumab
- chikungunya vaccine, live (cvx 317)
- chikungunya vaccine, recombinant (cvx 329)
- chloramphenicol
- chloramphenicol ophthalmic
- chloramphenicol otic
- cholera vaccine
- cholera vaccine, live
- cilostazol
- cimetidine
- ciprofloxacin
- citalopram
- cladribine
- clarithromycin
- clofazimine
- clomipramine
- clopidogrel
- clotrimazole
- clozapine
- cobicistat
- coccidioidin skin test
- colchicine
- conivaptan
- cosibelimab
- COVID-19 mRNA (Moderna) vaccine
- COVID-19 mRNA (Pfizer) vaccine
- crizotinib
- cyclosporine
D
- dabigatran
- dalteparin
- danaparoid
- danazol
- daridorexant
- darunavir
- dasatinib
- deferasirox
- deferiprone
- defibrotide
- delavirdine
- dengue vaccine
- denosumab
- deoxycholic acid
- desirudin
- desvenlafaxine
- deucravacitinib
- dexamethasone
- dexfenfluramine
- dextran 1
- dextran, high molecular weight
- dextran, low molecular weight
- diclofenac
- diclofenac ophthalmic
- diclofenac topical
- dicumarol
- diflunisal
- digoxin
- diltiazem
- dimethyl fumarate
- dipyridamole
- diroximel fumarate
- dostarlimab
- dronedarone
- drotrecogin alfa
- duloxetine
- durvalumab
- duvelisib
E
- edoxaban
- efalizumab
- efavirenz
- efbemalenograstim alfa
- eflapegrastim
- elafibranor
- elagolix
- emapalumab
- encorafenib
- enoxaparin
- entrectinib
- enzalutamide
- epoprostenol
- eptifibatide
- erlotinib
- erythromycin
- escitalopram
- etanercept
- etodolac
- etrasimod
- etravirine
- everolimus
F
- fedratinib
- felbamate
- fenfluramine
- fenoprofen
- fexinidazole
- fexofenadine
- fidaxomicin
- filgrastim
- fingolimod
- flax
- fluconazole
- fluoxetine
- flurbiprofen
- flurbiprofen ophthalmic
- fluvoxamine
- fondaparinux
- fosamprenavir
- fosaprepitant
- fosphenytoin
G
- ganciclovir
- gilteritinib
- givinostat
- glofitamab
- goldenseal
- golimumab
- grepafloxacin
- griseofulvin
- guselkumab
H
- haemophilus b conjugate (hboc) vaccine
- haemophilus b conjugate (prp-omp) vaccine
- haemophilus b conjugate (prp-t) vaccine
- hemin
- heparin
- heparin flush
- hepatitis a adult vaccine
- hepatitis a pediatric vaccine
- hepatitis b adult vaccine
- hepatitis b pediatric vaccine
- histoplasmin
- horse chestnut
- human papillomavirus vaccine
I
- ibritumomab
- ibuprofen
- idelalisib
- iloprost
- imatinib
- indinavir
- indomethacin
- infliximab
- influenza virus vaccine, h1n1, inactivated
- influenza virus vaccine, h1n1, live
- influenza virus vaccine, h5n1
- influenza virus vaccine, inactivated
- influenza virus vaccine, live
- inotersen
- iodine i 131 tositumomab
- ipilimumab
- iptacopan
- isoniazid
- itraconazole
- ivacaftor
- ivosidenib
- ixekizumab
J
K
L
- lactobacillus acidophilus
- lactobacillus reuteri
- lactobacillus rhamnosus
- lactobacillus rhamnosus gg
- lanreotide
- lapatinib
- larotrectinib
- lazertinib
- lefamulin
- leflunomide
- lenacapavir
- lenalidomide
- lepirudin
- letermovir
- levoketoconazole
- levomilnacipran
- linagliptin
- lomitapide
- lonafarnib
- lonapegsomatropin
- loncastuximab tesirine
- loperamide
- lorlatinib
- lusutrombopag
- lyme disease vaccine
M
- maraviroc
- mavacamten
- mavorixafor
- measles virus vaccine
- meclofenamate
- mefenamic acid
- meloxicam
- meningococcal conjugate vaccine
- meningococcal group acwy conjugate-group b vaccine (cvx 316)
- meningococcal group B vaccine
- meningococcal polysaccharide vaccine
- mephobarbital
- methadone
- mibefradil
- miconazole
- mifepristone
- milnacipran
- mirikizumab
- mitapivat
- mitotane
- mixed respiratory vaccine
- mobocertinib
- modafinil
- monomethyl fumarate
- morphine
- mumps skin test antigen
- mumps virus vaccine
N
- nabumetone
- nadofaragene firadenovec
- nafcillin
- naproxen
- natalizumab
- nefazodone
- nelfinavir
- nemolizumab
- nepafenac ophthalmic
- nevirapine
- nifedipine
- nilotinib
- nintedanib
- niraparib
- nirogacestat
- nivolumab
O
- ocrelizumab
- octreotide
- olaparib
- olutasidenib
- omacetaxine
- omaveloxolone
- oritavancin
- osilodrostat
- osimertinib
- oxaprozin
- oxcarbazepine
- ozanimod
P
- pacritinib
- palbociclib
- palifermin
- panobinostat
- paroxetine
- pasireotide
- pazopanib
- pegfilgrastim
- pembrolizumab
- pentobarbital
- pentosan polysulfate sodium
- pertussis, acellular
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- piroxicam
- pirtobrutinib
- plague vaccine
- plicamycin
- pneumococcal 13-valent vaccine
- pneumococcal 15-valent conjugate vaccine
- pneumococcal 20-valent conjugate vaccine
- pneumococcal 21-valent conjugate vaccine
- pneumococcal 23-polyvalent vaccine
- pneumococcal 7-valent vaccine
- poliovirus vaccine, inactivated
- poliovirus vaccine, live, trivalent
- ponatinib
- ponesimod
- posaconazole
- pralsetinib
- prasugrel
- primidone
- prucalopride
Q
R
- rabies vaccine, human diploid cell
- rabies vaccine, purified chick embryo cell
- radium 223 dichloride
- ramucirumab
- ranolazine
- regorafenib
- relugolix
- remdesivir
- repotrectinib
- reteplase
- retifanlimab
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rifaximin
- rilonacept
- rimegepant
- ripretinib
- risankizumab
- ritlecitinib
- ritonavir
- rivaroxaban
- roflumilast
- ropeginterferon alfa-2b
- rotavirus vaccine
- rsv vaccine pref3, recombinant
- rsv vaccine, mrna
- rsv vaccine, pref a-pref b, recombinant
- rubella virus vaccine
- rucaparib
- rufinamide
- ruxolitinib
S
- saccharomyces boulardii lyo
- samarium sm 153 lexidronam
- saquinavir
- sargramostim
- sarilumab
- sars-cov-2 (covid-19) ad26 vaccine, recombinant
- sars-cov-2 (covid-19) chadox1 vaccine, recombinant
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 308)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)
- sars-cov-2 (covid-19) nvx-cov2373 vaccine, recombinant
- sars-cov-2 (covid-19) rs-nanoparticle vaccine, recombinant
- sars-cov-2 mrna (tozinameran 5y-11y) vaccine
- sars-cov-2 mrna (tozinameran 6m-4y) vaccine
- sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine
- sars-cov-2 mrna (tozinameran) vaccine
- sars-cov-2 mrna-1273 (6m-5y) vaccine
- sars-cov-2 mrna-1273 (6y-11y) vaccine
- sars-cov-2 mrna-1273 (booster only) vaccine
- sars-cov-2 nvx-cov2373 vaccine, recomb (cvx 313)
- sars-cov-2 pres dtm (booster only) vaccine, recombinant
- satralizumab
- saxagliptin
- secobarbital
- secukinumab
- seladelpar
- selpercatinib
- sertraline
- sibutramine
- silodosin
- siltuximab
- siponimod
- sipuleucel-T
- sirolimus
- sitagliptin
- skin test antigens, multiple
- smallpox and mpox vaccine
- smallpox vaccine
- sodium phosphate p32
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotorasib
- st. john's wort
- staphage lysate (spl)
- stiripentol
- streptococcus salivarius
- streptokinase
- strontium-89 chloride
- sulfinpyrazone
- sulindac
- sunitinib
- suprofen ophthalmic
- suzetrigine
T
- tacrolimus
- talazoparib
- talimogene laherparepvec
- tazemetostat
- tbo-filgrastim
- tecovirimat
- telaprevir
- telithromycin
- tenecteplase
- tepotinib
- terfenadine
- teriflunomide
- tetanus toxoid
- ticagrelor
- tick-borne encephalitis (inactivated) pediatric vaccine
- tick-borne encephalitis (inactivated) vaccine
- ticlopidine
- tildrakizumab
- tinzaparin
- tipranavir
- tirofiban
- tislelizumab
- tocilizumab
- tofacitinib
- tolmetin
- tolvaptan
- topotecan
- toripalimab
- tositumomab
- tovorafenib
- tremelimumab
- treosulfan
- treprostinil
- trichophyton skin test
- trofinetide
- troglitazone
- troleandomycin
- tuberculin purified protein derivative
- tucatinib
- typhoid vaccine, inactivated
- typhoid vaccine, live
U
V
- vadadustat
- valganciclovir
- varicella virus vaccine
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- vibegron
- vilazodone
- viloxazine
- vonoprazan
- vorapaxar
- vorasidenib
- voriconazole
- vortioxetine
- voxelotor
W
Y
Z
Ibrutinib alcohol/food interactions
There are 3 alcohol/food interactions with ibrutinib.
Ibrutinib disease interactions
There are 8 disease interactions with ibrutinib which include:
- arrhythmias
- bleeding
- cytopenia
- hepatic impairment
- hypertension
- infections
- renal impairment
- tumor lysis syndrome
Report options
QR code containing a link to this page
More about ibrutinib
- ibrutinib consumer information
- Check interactions
- Compare alternatives
- Reviews (86)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: BTK inhibitors
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Deltasone
Deltasone is used for acute lymphocytic leukemia, adrenocortical insufficiency, allergic reactions ...
Reviews & ratings
Rituxan
Rituxan infusion is used to treat certain leukemias and lymphomas and some non-cancer conditions ...
Reviews & ratings
Featured
Jaypirca
Jaypirca (pirtobrutinib) is a cancer medicine used to treat types of CLL, SLL, and MCL. Includes ...
Reviews & ratings
Kesimpta
Kesimpta (ofatumumab) is used to treat relapsing forms of multiple sclerosis. Includes Kesimpta ...
Reviews & ratings
Jakafi
Jakafi is used to treat certain types of myelofibrosis or polycythemia vera in adults, and certain ...
Reviews & ratings
Imbruvica
Imbruvica (ibrutinib) is used to treat chronic lymphocytic leukemia (CLL), small lymphocytic ...
Reviews & ratings
Venetoclax
Venetoclax (brand name Venclexta) may be used to treat CLL, SLL, or AML in those aged 75 years or ...
Reviews & ratings
Cyclophosphamide
Cyclophosphamide systemic is used for acute lymphocytic leukemia, acute nonlymphocytic leukemia ...
Reviews & ratings
Rituximab
Rituximab infusion is used to treat certain leukemias and lymphomas and some non-cancer conditions ...
Reviews & ratings
Methotrexate
Methotrexate is used to treat certain types of cancer of the breast, skin, head and neck, or lung ...
Reviews & ratings
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
