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Diphenhydramine / guaifenesin Drug Interactions

A total of 383 drugs are known to interact with diphenhydramine / guaifenesin.

  • 11 major drug interactions
  • 370 moderate drug interactions
  • 2 minor drug interactions

Show all medications in the database that may interact with diphenhydramine / guaifenesin.

Check for interactions

Type in a drug name to check for interactions with diphenhydramine / guaifenesin.

Most frequently checked interactions

View interaction reports for diphenhydramine / guaifenesin and the medicines listed below.

Diphenhydramine / guaifenesin alcohol/food interactions

There is 1 alcohol/food interaction with diphenhydramine / guaifenesin

Diphenhydramine / guaifenesin disease interactions

There are 8 disease interactions with diphenhydramine / guaifenesin which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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