Diphenhydramine / guaifenesin Drug Interactions
A total of 801 drugs (4781 brand and generic names) are known to interact with diphenhydramine / guaifenesin.
- 33 major drug interactions (160 brand and generic names)
- 765 moderate drug interactions (4611 brand and generic names)
- 3 minor drug interactions (10 brand and generic names)
Check for interactions with diphenhydramine / guaifenesin
Common medications checked in combination with diphenhydramine / guaifenesin
- Adderall (amphetamine / dextroamphetamine)
- Afrin (oxymetazoline nasal)
- Aspirin Low Strength (aspirin)
- Centrum Singles-Beta Carotene (beta-carotene)
- Clomid (clomiphene)
- Concerta (methylphenidate)
- Folic Acid XTRA (multivitamin)
- GenRx Tramadol (tramadol)
- Januvia (sitagliptin)
- Lipofen (fenofibrate)
- Nexium (esomeprazole)
- Pepto-Bismol (bismuth subsalicylate)
- Prenatal 19 (multivitamin, prenatal)
- Prenatal Multivitamins (multivitamin, prenatal)
- Prevacid (lansoprazole)
- Pyridium (phenazopyridine)
- QNASL (beclomethasone nasal)
- Ultram ER (tramadol)
- Vitamin B Complex 100 (multivitamin)
- Zoloft (sertraline)
diphenhydramine / guaifenesin alcohol/food Interactions
There is 1 alcohol/food interaction with diphenhydramine / guaifenesin
diphenhydramine / guaifenesin disease Interactions
There are 8 disease interactions with diphenhydramine / guaifenesin which include:
- Anticholinergic Effects
- Depression
- Asthma/Copd
- Cardiovascular
- Renal/Liver Disease
- Glaucoma
- Liver Disease
- Resp Depression
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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