Tranquil Nighttime Sleep Aid Interactions
There are 449 drugs known to interact with Tranquil Nighttime Sleep Aid (diphenhydramine), along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 15 are major, 431 are moderate, and 3 are minor.
- View all 449 medications that may interact with Tranquil Nighttime Sleep Aid
- View Tranquil Nighttime Sleep Aid alcohol/food interactions (1)
- View Tranquil Nighttime Sleep Aid disease interactions (8)
Most frequently checked interactions
View interaction reports for Tranquil Nighttime Sleep Aid (diphenhydramine) and the medicines listed below.
- aspirin
- Aspirin Low Strength (aspirin)
- atorvastatin
- biotin
- calcium carbonate
- cyclobenzaprine
- Cymbalta (duloxetine)
- divalproex sodium
- ergocalciferol
- finasteride
- fluconazole
- furosemide
- gabapentin
- Iron Sulfate (ferrous sulfate)
- Lamictal (lamotrigine)
- levothyroxine
- Lipitor (atorvastatin)
- lisinopril
- lorazepam
- losartan
- Lunesta (eszopiclone)
- magnesium oxide
- melatonin
- metformin
- metoprolol
- omeprazole
- oxybutynin
- Pristiq (desvenlafaxine)
- sertraline
- Vitamin D3 (cholecalciferol)
Tranquil Nighttime Sleep Aid alcohol/food interactions
There is 1 alcohol/food interaction with Tranquil Nighttime Sleep Aid (diphenhydramine).
Tranquil Nighttime Sleep Aid disease interactions
There are 8 disease interactions with Tranquil Nighttime Sleep Aid (diphenhydramine) which include:
- depression
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
Report options
More about Tranquil Nighttime Sleep Aid (diphenhydramine)
- Compare alternatives
- Imprints, shape & color data
- Latest FDA alerts (2)
- Side effects
- Dosage information
- During pregnancy
- Drug class: anticholinergic antiemetics
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.