Histaprin Interactions
There are 449 drugs known to interact with Histaprin (diphenhydramine), along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 15 are major, 431 are moderate, and 3 are minor.
- View all 449 medications that may interact with Histaprin
- View Histaprin alcohol/food interactions (1)
- View Histaprin disease interactions (8)
Most frequently checked interactions
View interaction reports for Histaprin (diphenhydramine) and the medicines listed below.
- acetaminophen
- acetaminophen
- albuterol
- albuterol
- Alka-Seltzer Fruit Chews (Antacid) (calcium carbonate)
- Alka-Seltzer Fruit Chews (Antacid) (calcium carbonate)
- Alka-Seltzer Heartburn ReliefChews (calcium carbonate)
- Alka-Seltzer Heartburn ReliefChews (calcium carbonate)
- Allegra (fexofenadine)
- Allegra (fexofenadine)
- aluminum hydroxide / magnesium hydroxide / simethicone
- aluminum hydroxide / magnesium hydroxide / simethicone
- amitriptyline / chlordiazepoxide
- amitriptyline / chlordiazepoxide
- ampicillin / sulbactam
- ampicillin / sulbactam
- atenolol
- atenolol
- azithromycin
- azithromycin
- beclomethasone
- beclomethasone
- bisoprolol
- bisoprolol
- hydrochlorothiazide / irbesartan
- hydrochlorothiazide / irbesartan
- montelukast
- montelukast
- Ventolin (albuterol)
- Ventolin (albuterol)
Histaprin alcohol/food interactions
There is 1 alcohol/food interaction with Histaprin (diphenhydramine).
Histaprin disease interactions
There are 8 disease interactions with Histaprin (diphenhydramine) which include:
- depression
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
Report options
More about Histaprin (diphenhydramine)
- Compare alternatives
- Latest FDA alerts (2)
- Side effects
- Dosage information
- During pregnancy or Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.