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Diltiazem Drug Interactions

Currently displaying 139 drugs known to have a major interaction with diltiazem.

See also: The most common drugs checked in combination with this medicine.

Check for interactions

Type in a drug name to check for interactions with diltiazem.

Medications known to interact with diltiazem

    • carbamazepine (Tegretol, Carbatrol, Epitol, Tegretol XR, Equetro, Carnexiv)
    • carbinoxamine / hydrocodone / phenylephrine (Excof, Donatussin MAX, Excof-SF, Max HC)
    • carbinoxamine / hydrocodone / pseudoephedrine (Tri-Vent HC, Histex HC, Mintex HC)
    • carteolol (Cartrol)
    • carteolol ophthalmic (Ocupress)
    • carvedilol (Coreg, Coreg CR)
    • chlorpheniramine / guaifenesin / hydrocodone / pseudoephedrine (Z-Tuss 2)
    • chlorpheniramine / hydrocodone (Tussionex Pennkinetic, TussiCaps, Hydrocodone GF, Novasus, Vituz, S-T Forte 2, HyTan)
    • chlorpheniramine / hydrocodone / phenylephrine (Hydrocodone CP, Hydrocodone HD, Iodal HD, Endotuss-HD, Hydro-PC II, Triant-HC, Endagen-HD, Chemdal HD, Rindal-HD, Ed-TLC, Efasin-HD, Guiaphen HD, Mintuss MS, Vanex-HD, Chemdal HD Plus, Nasatuss, Iotussin HC, Chlorgest HD, Ed-Tuss HC, Cyndal HD, Hyphen-HD, Tuss-PD, KG-Dal HD, Ditussin-HC, Chemtussin HC, Exo-Tuss, Endal-HD Plus, Enplus-HD, Comtussin HC, Tuss-HC, Ventuss Syrup, Maxi-Tuss SA, Maxi-Tuss HC, Histinex HC, Coughtuss, KG-Dal HD Plus, Highland HC, Uni Tuss HC, H-C Tussive, Histussin HC Liquid, Cytuss HC, Tuss-DS, Efasin-HD Plus, Quindal HD Plus, Quindal HD, Hi-Tuss HC, Chlorphen HD, Duradal HD, Liquitussin HC Syrup, Tussive HC, B-Tuss, Hydron CP, De-Chlor HD, De-Chlor HC, Atuss MS, Hydro-PC II Plus, Uni-Tricof HC, Rindal HD Plus, Echotuss-HC, Phendal-HD, Relacon-HC NR, Tusana-D, Neo HC, Poly-Tussin HD, Liquicough HC, Relasin-HC, DroTuss-CP, Z-Cof HC, Maxi-Tuss HCX, Relacon-HC)
    • chlorpheniramine / hydrocodone / pseudoephedrine (Hydron PCS, Zutripro, Notuss-Forte, Notuss, Detuss, Histinex PV, JayCof-HC, Pediatex HC, Tussend, Welltuss HC, Hexatussin, Hyphed, Tussin-V, Q-V Tussin, A-G Tussin, KG-Tussin, P-V-Tussin Syrup, Hydrotuss HC, Hydrocof-HC, Cordron-HC, Cordron-HC NR, Atuss HD, Atuss HS)
    • cilostazol (Pletal)
    • cisapride (Propulsid)
    • cobimetinib (Cotellic)
    • colchicine (Colcrys, Mitigare, Gloperba)
    • colchicine / probenecid (Probenecid and Colchicine, Proben-C)
    • guaifenesin / hydrocodone (Hydrocod-GF, Vitussin Expectorant, Narcof, Condasin, Obredon, Vicodin Tuss, Monte-G HC, Flowtuss, CodiCLEAR DH, Maxi-Tuss HCG, EndaCof-Tab, Ztuss ZT, Tusso-HC, Execlear, Hycotuss Expectorant, Pneumotussin HC, Propatuss Expectorant, Kwelcof, Vi-Q-Tuss, Co-Tussin, Codotuss, Fentuss Expectorant, Co-Tuss V Expectorant, Vicoclear, Endacof XP, Hycosin Expectorant, Vicotuss, G-Tuss, Hycoclar Tuss, Cotuss V, Hydrotuss, Gua HC, Hycoclear, Medcodin, Vortex, Pneumotussin 2.5, Entuss, Pneumotussin, Tusso-DF, Execof, Pancof XP, Touro HC, Xpect-HC, Atuss HX, Extendryl HC, Hydro-Tussin HG, Canges-XP, Z-Cof HCX, Tussicle, A-Cof DH, Relasin-HCX)
    • guaifenesin / hydrocodone / pheniramine / phenylephrine / phenylpropanolamine (S-T Forte)
    • guaifenesin / hydrocodone / pheniramine / phenylpropanolamine / pyrilamine
    • guaifenesin / hydrocodone / phenylephrine (Mintuss G, Atuss G, Ambi 5/15/100, Tussafed-HC, Levall 5.0, Hydro GP, De-Chlor G, Dynatuss HC, Tussafed-HCG, Uni-Lev 5.0, Crantex HC, Duratuss HD, Simuc-HD, Gentex HC, Donatussin DC, Guiaplex HC, Exetuss-HC, Qual-Tussin DC, Nariz HC, MonteFlu HC, Nazarin HC, HydroFed)
    • guaifenesin / hydrocodone / pseudoephedrine (Hycofenix, Entuss-D JR, Decotuss-HD, Vanex Expectorant, Tussadur-HD, Tussend Expectorant, Detussin Expectorant, Tussgen Expectorant, SRC Expectorant, Nalex Expectorant, Deconamine CX, Poly-Tussin XP, Entuss-D, Hydrotussin HD, KG-Tuss HD, Medtuss HD, Spantuss HD, Vanacon, Su-Tuss HD Elixir, Tussafin Liquid, Hytussin Expectorant, Drituss HD, Hydro-Tuss XP, Dynex HD, Entex HC, Pseudatex HC)
    • guanfacine (Intuniv, Tenex)
    • olaparib (Lynparza)
    • oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, Oxyfast, Oxecta, RoxyBond, Percolone, Dazidox, Oxydose, M-Oxy, ETH-Oxydose, Endocodone, Roxicodone Intensol)

    Diltiazem alcohol/food interactions

    There are 2 alcohol/food interactions with diltiazem

    Diltiazem disease interactions

    There are 9 disease interactions with diltiazem which include:

    Drug Interaction Classification

    These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
    Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
    Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
    Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
    Unknown No interaction information available.

    Further information

    Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.