Natrol Sleep'n Restore Drug Interactions
Currently displaying a list of 744 drugs known to interact with Natrol Sleep'n Restore (calcium carbonate / melatonin / valerian / vitamin e).
- 19 major drug interactions
- 602 moderate drug interactions
- 123 minor drug interactions
Medications known to interact with Natrol Sleep'n Restore
Note: Showing generic names only.
A
- abametapir topical
- abatacept
- abciximab
- abemaciclib
- abrocitinib
- acalabrutinib
- acebutolol
- acetohexamide
- acetylcarbromal
- acrivastine
- adalimumab
- afamitresgene autoleucel
- alefacept
- alendronate
- alfentanil
- allopurinol
- alprazolam
- altretamine
- amiodarone
- amisulpride
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amphetamine
- amprenavir
- anagrelide
- anakinra
- anifrolumab
- anisindione
- anti-thymocyte globulin (rabbit)
- antithrombin (recombinant)
- antithrombin iii
- apalutamide
- apixaban
- apomorphine
- apraclonidine ophthalmic
- ardeparin
- argatroban
- aripiprazole
- armodafinil
- arsenic trioxide
- asenapine
- aspirin
- atazanavir
- atenolol
- atropine
- avacopan
- axicabtagene ciloleucel
- axitinib
- azacitidine
- azatadine
- azathioprine
- azelastine nasal
B
- bacampicillin
- baclofen
- baloxavir marboxil
- baricitinib
- basiliximab
- beclomethasone
- belatacept
- belimumab
- belumosudil
- benazepril
- bendamustine
- bendroflumethiazide
- benzphetamine
- benzthiazide
- benztropine
- bepridil
- betamethasone
- betaxolol
- betrixaban
- bimekizumab
- biperiden
- bisacodyl
- bisoprolol
- bivalirudin
- bleomycin
- blinatumomab
- bortezomib
- bosutinib
- brexanolone
- brexpiprazole
- brexucabtagene autoleucel
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- brodalumab
- bromocriptine
- brompheniramine
- budesonide
- buprenorphine
- bupropion
- buspirone
- busulfan
- butabarbital
- butalbital
- butorphanol
C
- cabazitaxel
- cabotegravir
- caffeine
- calcipotriene topical
- calcitriol topical
- canakinumab
- cangrelor
- cannabidiol
- cannabis
- capecitabine
- caplacizumab
- capmatinib
- captopril
- carbamazepine
- carbetapentane
- carbinoxamine
- carbonyl iron
- carboplatin
- carfilzomib
- cariprazine
- carisoprodol
- carmustine
- carteolol
- carvedilol
- cefditoren
- cefpodoxime
- cefuroxime
- cenobamate
- ceritinib
- certolizumab
- cetirizine
- chlophedianol
- chloral hydrate
- chlorambucil
- chlorcyclizine
- chlordiazepoxide
- chlormezanone
- chloroquine
- chlorothiazide
- chlorotrianisene
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorpropamide
- chlorthalidone
- chlorzoxazone
- cholestyramine
- choline salicylate
- cilostazol
- ciltacabtagene autoleucel
- cimetidine
- cinoxacin
- ciprofloxacin
- cisplatin
- citalopram
- cladribine
- clemastine
- clevidipine
- clobazam
- clofarabine
- clomipramine
- clonazepam
- clonidine
- clopidogrel
- clorazepate
- clozapine
- codeine
- colesevelam
- colestipol
- conjugated estrogens
- conjugated estrogens topical
- cortisone
- crovalimab
- cyclizine
- cyclobenzaprine
- cyclophosphamide
- cyclosporine
- cyproheptadine
- cytarabine
- cytarabine liposomal
D
- dabigatran
- dabrafenib
- dacarbazine
- daclizumab
- dactinomycin
- dalteparin
- danaparoid
- danicopan
- dantrolene
- daridorexant
- darifenacin
- dasatinib
- datopotamab deruxtecan
- daunorubicin
- daunorubicin liposomal
- decitabine
- deferasirox
- deferiprone
- defibrotide
- deflazacort
- dehydroepiandrosterone
- delafloxacin
- delavirdine
- demeclocycline
- desipramine
- desirudin
- desvenlafaxine
- deucravacitinib
- deutetrabenazine
- dexamethasone
- dexbrompheniramine
- dexchlorpheniramine
- dexmedetomidine
- dextroamphetamine
- dextromethorphan
- dezocine
- diazepam
- dicumarol
- diethylstilbestrol
- difelikefalin
- diflunisal
- digitoxin
- digoxin
- diltiazem
- dimenhydrinate
- dimethyl fumarate
- diphenhydramine
- dipyridamole
- diroximel fumarate
- divalproex sodium
- docetaxel
- dolutegravir
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- doxycycline
- doxylamine
- dronabinol
- droperidol
- drotrecogin alfa
- duloxetine
- dupilumab
E
- echinacea
- eculizumab
- edoxaban
- efalizumab
- efavirenz
- efgartigimod alfa
- eltrombopag
- elvitegravir
- enalapril
- enalaprilat
- enasidenib
- enfortumab vedotin
- enoxacin
- enoxaparin
- entacapone
- epirubicin
- epoprostenol
- eptifibatide
- erdafitinib
- eribulin
- erlotinib
- erythromycin
- escitalopram
- esketamine
- eslicarbazepine
- estazolam
- esterified estrogens
- estradiol
- estramustine
- estrone
- estropipate
- eszopiclone
- etanercept
- ethanol
- ethchlorvynol
- ethinyl estradiol
- ethosuximide
- ethotoin
- etidronate
- etoposide
- etrasimod
- everolimus
- ezogabine
F
- famotidine
- felbamate
- felodipine
- fenfluramine
- fentanyl
- ferric carboxymaltose
- ferric derisomaltose
- ferric maltol
- ferric pyrophosphate
- ferrous fumarate
- ferrous gluconate
- ferrous sulfate
- ferumoxytol
- fexinidazole
- flavoxate
- flibanserin
- floxuridine
- fluconazole
- fludarabine
- fludrocortisone
- fluorouracil
- fluoxetine
- fluphenazine
- flurazepam
- fluvoxamine
- fondaparinux
- fosinopril
- fosphenytoin
- fospropofol
- fruquintinib
G
- gabapentin
- gabapentin enacarbil
- ganaxolone
- gatifloxacin
- gefitinib
- gemcitabine
- gemfibrozil
- gemifloxacin
- givinostat
- givosiran
- glimepiride
- glipizide
- glyburide
- golimumab
- grepafloxacin
- guanfacine
- guselkumab
H
- halazepam
- haloperidol
- heme iron polypeptide
- heparin
- heroin
- hydrochlorothiazide
- hydrocodone
- hydrocortisone
- hydroflumethiazide
- hydromorphone
- hydroxychloroquine
- hydroxyprogesterone
- hydroxyurea
- hydroxyzine
I
- ibandronate
- ibritumomab
- idarubicin
- ifosfamide
- iloperidone
- iloprost
- imatinib
- imetelstat
- imipramine
- indapamide
- infigratinib
- infliximab
- interferon alfa-2a
- interferon alfa-2b
- iptacopan
- irinotecan
- irinotecan liposomal
- iron bisglycinate
- iron dextran
- iron polysaccharide
- iron protein succinylate
- iron sucrose
- isocarboxazid
- isoniazid
- isradipine
- itraconazole
- ixabepilone
- ixazomib
- ixekizumab
K
L
- labetalol
- lactulose
- lamotrigine
- lasmiditan
- leflunomide
- lemborexant
- leniolisib
- lepirudin
- levamlodipine
- levetiracetam
- levocetirizine
- levodopa
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- levorphanol
- levothyroxine
- levothyroxine / liothyronine
- lidocaine
- lifileucel
- liothyronine
- liotrix
- lisdexamfetamine
- lisinopril
- lithium
- lofexidine
- lomefloxacin
- lomustine
- loncastuximab tesirine
- lorazepam
- loxapine
- lumateperone
- lurasidone
- lurbinectedin
- lutetium lu 177 dotatate
- lutetium lu 177 vipivotide tetraxetan
- lymphocyte immune globulin, anti-thy (equine)
M
- magnesium salicylate
- maprotiline
- maralixibat
- mechlorethamine
- meclizine
- melphalan
- melphalan flufenamide
- meperidine
- mephenytoin
- mephobarbital
- meprobamate
- mercaptopurine
- mesoridazine
- metaxalone
- methadone
- methamphetamine
- methdilazine
- methenamine
- methocarbamol
- methohexital
- methotrexate
- methotrimeprazine
- methoxsalen
- methsuximide
- methyclothiazide
- methyldopa
- methylprednisolone
- metoclopramide
- metolazone
- metoprolol
- metyrosine
- mexiletine
- mibefradil
- midazolam
- minocycline
- mirikizumab
- mirtazapine
- misoprostol
- mitomycin
- mitotane
- mitoxantrone
- modafinil
- moexipril
- molindone
- momelotinib
- morphine
- morphine liposomal
- moxifloxacin
- multivitamin with iron
- multivitamin with iron and fluoride
- multivitamin, prenatal
- muromonab-cd3
- mycophenolate mofetil
- mycophenolic acid
N
- nabilone
- nadolol
- nalbuphine
- nalidixic acid
- naproxen
- natalizumab
- nebivolol
- nefazodone
- nelarabine
- neratinib
- nicardipine
- niclosamide
- nicotine
- nifedipine
- nilotinib
- nimodipine
- niraparib
- nirogacestat
- nisoldipine
- nizatidine
- norfloxacin
- nortriptyline
O
- obeticholic acid
- ocrelizumab
- odevixibat
- ofloxacin
- olanzapine
- olaparib
- oliceridine
- olopatadine nasal
- omadacycline
- omalizumab
- omeprazole
- opicapone
- opium
- orlistat
- orphenadrine
- osilodrostat
- osimertinib
- oxaliplatin
- oxazepam
- oxcarbazepine
- oxycodone
- oxymorphone
- oxytetracycline
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- paliperidone
- pancreatin
- pancrelipase
- paraldehyde
- paramethadione
- paroxetine
- patiromer
- pazopanib
- pegcetacoplan
- peginterferon alfa-2a
- peginterferon alfa-2b
- pemetrexed
- penbutolol
- penicillamine
- pentazocine
- pentobarbital
- peppermint oil
- perampanel
- pergolide
- perindopril
- perphenazine
- pexidartinib
- phenacemide
- phenelzine
- phenindamine
- phenobarbital
- phensuximide
- phenytoin
- pimozide
- pindolol
- plicamycin
- polythiazide
- ponatinib
- ponesimod
- porfimer
- pozelimab
- pralatrexate
- pramipexole
- prasugrel
- prednisolone
- prednisone
- pregabalin
- primaquine
- primidone
- procarbazine
- prochlorperazine
- procyclidine
- proguanil
- promazine
- promethazine
- propafenone
- propantheline
- propiomazine
- propofol
- propoxyphene
- propranolol
- protein c
- protriptyline
- pyrilamine
- pyrimethamine
Q
R
- raltegravir
- ramelteon
- ramipril
- ranitidine
- ranitidine bismuth citrate
- rasagiline
- ravulizumab
- remifentanil
- remimazolam
- ribociclib
- rifampin
- rilonacept
- rilpivirine
- riociguat
- risankizumab
- risedronate
- risperidone
- ritlecitinib
- ritonavir
- rituximab
- rivaroxaban
- rofecoxib
- romidepsin
- ropinirole
- ropivacaine
- rosuvastatin
- rotigotine
- rozanolixizumab
- rucaparib
- rufinamide
S
- sacituzumab govitecan
- safinamide
- salsalate
- sarecycline
- sarilumab
- satralizumab
- scopolamine
- secobarbital
- secukinumab
- selegiline
- selpercatinib
- selumetinib
- sertraline
- sevelamer
- sibutramine
- siltuximab
- siponimod
- sirolimus
- sirolimus topical
- sodium ferric gluconate complex
- sodium oxybate
- sodium polystyrene sulfonate
- sodium salicylate
- sodium thiosalicylate
- sotalol
- sotorasib
- sparfloxacin
- sparsentan
- spesolimab
- st. john's wort
- stiripentol
- streptozocin
- strontium-89 chloride
- sucralfate
- sufentanil
- sulfinpyrazone
- sutimlimab
- suvorexant
T
- tacrolimus
- tapentadol
- tasimelteon
- temazepam
- temozolomide
- temsirolimus
- teniposide
- teplizumab
- teriflunomide
- tetrabenazine
- tetracycline
- thalidomide
- thiabendazole
- thiethylperazine
- thioguanine
- thiopental
- thioridazine
- thiotepa
- thiothixene
- thyroid desiccated
- tiagabine
- ticagrelor
- ticlopidine
- tildrakizumab
- tiludronate
- timolol
- tinzaparin
- tipranavir
- tirofiban
- tirzepatide
- tizanidine
- tocilizumab
- tofacitinib
- tolazamide
- tolbutamide
- tolcapone
- topiramate
- topotecan
- trabectedin
- tramadol
- trandolapril
- tranylcypromine
- trazodone
- treosulfan
- treprostinil
- triamcinolone
- triazolam
- trichlormethiazide
- trientine
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- trovafloxacin
U
V
- vadadustat
- valbenazine
- valproic acid
- valrubicin
- vamorolone
- varenicline
- vedolizumab
- vemurafenib
- venlafaxine
- verapamil
- vigabatrin
- vilobelimab
- viloxazine
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- vismodegib
- voclosporin
- vorapaxar
- vorinostat
W
Z
Natrol Sleep'n Restore alcohol/food interactions
There are 3 alcohol/food interactions with Natrol Sleep'n Restore (calcium carbonate / melatonin / valerian / vitamin e).
Natrol Sleep'n Restore disease interactions
There are 10 disease interactions with Natrol Sleep'n Restore (calcium carbonate / melatonin / valerian / vitamin e) which include:
- depression
- phosphate calcifications
- cardiac contraction/conduction
- malabsorption
- renal dysfunction
- sarcoidosis
- hepatobiliary dysfunction
- glaucoma
- liver disease
- malabsorption syndromes
Report options
QR code containing a link to this page
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Ativan
Ativan is a benzodiazepine used to treat anxiety disorders or anxiety associated with depression ...
Reviews & ratings
Benadryl
Benadryl is an antihistamine and is used to treat sneezing, runny nose, itching and other ...
Reviews & ratings
Featured
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Reviews & ratings
Ambien
Ambien (zolpidem) is a prescription sedative used to treat insomnia, helping you fall asleep and ...
Reviews & ratings
Lunesta
Lunesta is a sedative and is used to treat insomnia. Lunesta's effects typically begin within 30 ...
Reviews & ratings
Eszopiclone
Eszopiclone (brand name Lunesta) is a sedative and is used to treat insomnia. Eszopiclone's effects ...
Reviews & ratings
Temazepam
Temazepam is used to treat insomnia (trouble sleeping). Learn about side effects, interactions and ...
Reviews & ratings
Doxepin
Doxepin systemic is used for anxiety, depression, insomnia, irritable bowel syndrome, major ...
Reviews & ratings
Zolpidem
Zolpidem is a sedative-hypnotic medicine used for the short-term treatment of insomnia (trouble ...
Reviews & ratings
Diphenhydramine
Diphenhydramine is an antihistamine used to treat sneezing, runny nose, itching, hives and other ...
Reviews & ratings
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.