Alka-Seltzer Extra Strength Interactions
There are 473 drugs known to interact with Alka-Seltzer Extra Strength (aspirin/citric acid/sodium bicarbonate), along with 11 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 69 are major, 335 are moderate, and 69 are minor.
- View all 473 medications that may interact with Alka-Seltzer Extra Strength
- View Alka-Seltzer Extra Strength alcohol/food interactions (2)
- View Alka-Seltzer Extra Strength disease interactions (11)
Most frequently checked interactions
View interaction reports for Alka-Seltzer Extra Strength (aspirin/citric acid/sodium bicarbonate) and the medicines listed below.
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- buspirone
- buspirone
- cyclobenzaprine
- cyclobenzaprine
- gabapentin
- gabapentin
- hydroxyzine
- hydroxyzine
- ibuprofen
- ibuprofen
- lisinopril
- lisinopril
- melatonin
- melatonin
- naproxen
- naproxen
- omeprazole
- omeprazole
- ondansetron
- ondansetron
- Pepto-Bismol (bismuth subsalicylate)
- Pepto-Bismol (bismuth subsalicylate)
- prednisone
- prednisone
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
Alka-Seltzer Extra Strength alcohol/food interactions
There are 2 alcohol/food interactions with Alka-Seltzer Extra Strength (aspirin/citric acid/sodium bicarbonate).
Alka-Seltzer Extra Strength disease interactions
There are 11 disease interactions with Alka-Seltzer Extra Strength (aspirin/citric acid/sodium bicarbonate) which include:
- sodium/water balance
- coagulation
- asthma
- GI toxicity
- renal dysfunction
- Reye's syndrome
- acid/base balance
- anemia
- dialysis
- G-6-PD deficiency
- hepatotoxicity
Report options
More about Alka-Seltzer Extra Strength (aspirin/citric acid/sodium bicarbonate)
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.