Otezla XR Interactions
There are 114 drugs known to interact with Otezla XR (apremilast), along with 3 disease interactions. Of the total drug interactions, 16 are major, 95 are moderate, and 3 are minor.
- View Otezla XR disease interactions (3)
Medications known to interact with Otezla XR
Note: Showing generic names only.
A
- abametapir topical
- abrocitinib
- allogeneic processed thymus tissue
- aminoglutethimide
- amobarbital
- apalutamide
- armodafinil
- atezolizumab
- avelumab
B
C
D
E
- echinacea
- efavirenz
- elacestrant
- elafibranor
- elagolix
- encorafenib
- enzalutamide
- eslicarbazepine
- etravirine
F
G
I
L
M
N
O
P
- pacritinib
- pembrolizumab
- penpulimab
- pentobarbital
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- pirtobrutinib
- pralsetinib
- pretomanid
- primidone
R
S
- sarecycline
- secobarbital
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sotorasib
- st. john's wort
- sulfinpyrazone
- suzetrigine
T
- tacrolimus topical
- talazoparib
- tazemetostat
- tecovirimat
- telotristat
- tislelizumab
- toripalimab
- tovorafenib
- tremelimumab
- trofinetide
- troglitazone
- tucatinib
U
V
Otezla XR disease interactions
There are 3 disease interactions with Otezla XR (apremilast) which include:
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.