Benadryl Cold Interactions
There are 654 drugs known to interact with Benadryl Cold (acetaminophen / diphenhydramine / pseudoephedrine), along with 17 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 36 are major, 601 are moderate, and 17 are minor.
- View all 654 medications that may interact with Benadryl Cold
- View Benadryl Cold alcohol/food interactions (2)
- View Benadryl Cold disease interactions (17)
Most frequently checked interactions
View interaction reports for Benadryl Cold (acetaminophen / diphenhydramine / pseudoephedrine) and the medicines listed below.
- Ambien (zolpidem)
- Ambien (zolpidem)
- aspirin
- aspirin
- Aspirin Low Strength (aspirin)
- Aspirin Low Strength (aspirin)
- atorvastatin
- atorvastatin
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- cetirizine
- cetirizine
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- levothyroxine
- levothyroxine
- montelukast
- montelukast
- omeprazole
- omeprazole
- ranitidine
- ranitidine
- Vitamin C (ascorbic acid)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Zofran (ondansetron)
- Zofran (ondansetron)
- Zyrtec (cetirizine)
- Zyrtec (cetirizine)
Benadryl Cold alcohol/food interactions
There are 2 alcohol/food interactions with Benadryl Cold (acetaminophen / diphenhydramine / pseudoephedrine).
Benadryl Cold disease interactions
There are 17 disease interactions with Benadryl Cold (acetaminophen / diphenhydramine / pseudoephedrine) which include:
- alcoholism
- liver disease
- depression
- cardiovascular disease
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- GI narrowing
- PKU
- BPH
- diabetes
- glaucoma
More about Benadryl Cold (acetaminophen / diphenhydramine / pseudoephedrine)
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.