Sudafed PE Severe Cold Interactions
There are 683 drugs known to interact with Sudafed PE Severe Cold (acetaminophen/diphenhydramine/phenylephrine), along with 15 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 50 are major, 619 are moderate, and 14 are minor.
- View all 683 medications that may interact with Sudafed PE Severe Cold
- View Sudafed PE Severe Cold alcohol/food interactions (3)
- View Sudafed PE Severe Cold disease interactions (15)
Most frequently checked interactions
View interaction reports for Sudafed PE Severe Cold (acetaminophen / diphenhydramine / phenylephrine) and the medicines listed below.
- Aleve (naproxen)
- amlodipine
- amoxicillin
- Azithromycin Dose Pack (azithromycin)
- benzonatate
- bupropion
- cephalexin
- Cipro (ciprofloxacin)
- clindamycin
- Crestor (rosuvastatin)
- doxycycline
- Fish Oil (omega-3 polyunsaturated fatty acids)
- hydrochlorothiazide
- ibuprofen
- Lexapro (escitalopram)
- lisinopril
- loratadine
- metformin
- metoprolol
- Mucinex DM (dextromethorphan / guaifenesin)
- multivitamin
- omeprazole
- prednisone
- tramadol
- Tylenol (acetaminophen)
- Vicks Dayquil Cold & Flu Relief (acetaminophen / dextromethorphan / phenylephrine)
- Vicks NyQuil Severe Cold & Flu (acetaminophen / dextromethorphan / doxylamine / phenylephrine)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
Sudafed PE Severe Cold alcohol/food interactions
There are 3 alcohol/food interactions with Sudafed PE Severe Cold (acetaminophen / diphenhydramine / phenylephrine).
Sudafed PE Severe Cold disease interactions
There are 15 disease interactions with Sudafed PE Severe Cold (acetaminophen / diphenhydramine / phenylephrine) which include:
- alcoholism
- liver disease
- depression
- cardiovascular disease
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- BPH
- diabetes
- glaucoma
Report options
More about Sudafed PE Severe Cold (acetaminophen / diphenhydramine / phenylephrine)
- Sudafed PE Severe Cold consumer information
- Compare alternatives
- Reviews (2)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
