Benadryl Allergy Plus Cold Interactions
There are 650 drugs known to interact with Benadryl Allergy Plus Cold (acetaminophen/diphenhydramine/phenylephrine), along with 15 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 48 are major, 588 are moderate, and 14 are minor.
- View all 650 medications that may interact with Benadryl Allergy Plus Cold
- View Benadryl Allergy Plus Cold alcohol/food interactions (2)
- View Benadryl Allergy Plus Cold disease interactions (15)
Most frequently checked interactions
View interaction reports for Benadryl Allergy Plus Cold (acetaminophen / diphenhydramine / phenylephrine) and the medicines listed below.
- albuterol
- Aleve (naproxen)
- amoxicillin
- aspirin
- Aspirin Low Strength (aspirin)
- atorvastatin
- Benadryl (diphenhydramine)
- clonazepam
- Fish Oil (omega-3 polyunsaturated fatty acids)
- gabapentin
- hydroxyzine
- ibuprofen
- lisinopril
- melatonin
- metformin
- omeprazole
- ondansetron
- oxycodone
- pantoprazole
- prednisone
- propranolol
- Prozac (fluoxetine)
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Benadryl Allergy Plus Cold alcohol/food interactions
There are 2 alcohol/food interactions with Benadryl Allergy Plus Cold (acetaminophen / diphenhydramine / phenylephrine).
Benadryl Allergy Plus Cold disease interactions
There are 15 disease interactions with Benadryl Allergy Plus Cold (acetaminophen / diphenhydramine / phenylephrine) which include:
- alcoholism
- liver disease
- depression
- cardiovascular disease
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- BPH
- diabetes
- glaucoma
Report options
More about Benadryl Allergy Plus Cold (acetaminophen / diphenhydramine / phenylephrine)
- Benadryl Allergy Plus Cold consumer information
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
