Pain Relief PM Extra Strength Interactions
There are 560 drugs known to interact with Pain Relief PM Extra Strength (acetaminophen / diphenhydramine), along with 11 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 23 are major, 522 are moderate, and 15 are minor.
- View all 560 medications that may interact with Pain Relief PM Extra Strength
- View Pain Relief PM Extra Strength alcohol/food interactions (2)
- View Pain Relief PM Extra Strength disease interactions (11)
Most frequently checked interactions
View interaction reports for Pain Relief PM Extra Strength (acetaminophen / diphenhydramine) and the medicines listed below.
- albuterol
- albuterol
- alprazolam
- alprazolam
- amlodipine
- amlodipine
- aspirin
- aspirin
- atorvastatin
- atorvastatin
- clopidogrel
- clopidogrel
- gabapentin
- gabapentin
- ibuprofen
- ibuprofen
- levothyroxine
- levothyroxine
- lisinopril
- lisinopril
- metoprolol
- metoprolol
- omeprazole
- omeprazole
- oxycodone
- oxycodone
- simvastatin
- simvastatin
- tramadol
- tramadol
Pain Relief PM Extra Strength alcohol/food interactions
There are 2 alcohol/food interactions with Pain Relief PM Extra Strength (acetaminophen / diphenhydramine).
Pain Relief PM Extra Strength disease interactions
There are 11 disease interactions with Pain Relief PM Extra Strength (acetaminophen / diphenhydramine) which include:
- alcoholism
- liver disease
- depression
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
Report options
More about Pain Relief PM Extra Strength (acetaminophen / diphenhydramine)
- Compare alternatives
- Imprints, shape & color data
- Side effects
- Dosage information
- During pregnancy
- Drug class: analgesic combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Diphenhydramine is an antihistamine used to treat sneezing, runny nose, itching, hives and other ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.