Acetaminophen/dextromethorphan/doxylamine/pseudoephedrine Interactions
There are 685 drugs known to interact with acetaminophen/dextromethorphan/doxylamine/pseudoephedrine, along with 17 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 103 are major, 563 are moderate, and 19 are minor.
- View all 685 medications that may interact with acetaminophen/dextromethorphan/doxylamine/pseudoephedrine
- View acetaminophen/dextromethorphan/doxylamine/pseudoephedrine alcohol/food interactions (2)
- View acetaminophen/dextromethorphan/doxylamine/pseudoephedrine disease interactions (17)
Most frequently checked interactions
View interaction reports for acetaminophen / dextromethorphan / doxylamine / pseudoephedrine and the medicines listed below.
- 5-HTP (5-hydroxytryptophan)
- Acidophilus (lactobacillus acidophilus)
- Acidophilus Probiotic Blend (lactobacillus acidophilus)
- Advil (ibuprofen)
- Advil Cold and Sinus (ibuprofen / pseudoephedrine)
- Advil PM (diphenhydramine / ibuprofen)
- Afluria Quadrivalent (influenza virus vaccine, inactivated)
- Alcohol (contained in alcoholic beverages) (ethanol)
- Aleve PM (diphenhydramine / naproxen)
- Alka-Seltzer Plus Maximum Strength Cold & Cough (acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine)
- Alka-Seltzer Plus Maximum Strength Day & Night Cold & Flu Liquid Gels (Night Formula) (acetaminophen / dextromethorphan / doxylamine / phenylephrine)
- Alka-Seltzer Plus Maximum Strength Day Cold & Flu Liquid Gels (acetaminophen / dextromethorphan / phenylephrine)
- Allegra (fexofenadine)
- Allegra-D 24 Hour Allergy & Congestion (fexofenadine / pseudoephedrine)
- Augmentin (amoxicillin / clavulanate)
- Augmentin XR (amoxicillin / clavulanate)
- Azo-Cranberry (cranberry)
- B 100 Complex (multivitamin)
- Backaid Max (acetaminophen / pamabrom)
- Bayer Back & Body (aspirin / caffeine)
- Benadryl (diphenhydramine)
- Benadryl Allergy Plus Congestion (diphenhydramine / phenylephrine)
- Benadryl Allergy Sinus (diphenhydramine / pseudoephedrine)
- Benadryl-D Allergy Plus Sinus (diphenhydramine / phenylephrine)
- Breo Ellipta (fluticasone / vilanterol)
- Celebrex (celecoxib)
- Cialis (tadalafil)
- Mucinex (guaifenesin)
- Synthroid (levothyroxine)
- Vitamin D3 (cholecalciferol)
Acetaminophen/dextromethorphan/doxylamine/pseudoephedrine alcohol/food interactions
There are 2 alcohol/food interactions with acetaminophen / dextromethorphan / doxylamine / pseudoephedrine.
Acetaminophen/dextromethorphan/doxylamine/pseudoephedrine disease interactions
There are 17 disease interactions with acetaminophen / dextromethorphan / doxylamine / pseudoephedrine which include:
- alcoholism
- liver disease
- depression
- cardiovascular disease
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- GI narrowing
- PKU
- BPH
- diabetes
- glaucoma
Report options
More about acetaminophen / dextromethorphan / doxylamine / pseudoephedrine
- Compare alternatives
- Reviews (5)
- Side effects
- Dosage information
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Benadryl
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Promethazine DM
Promethazine DM is used for allergic rhinitis, cold symptoms, cough
Ubrelvy
Ubrelvy (ubrogepant) tablets are used for the acute treatment of migraine. Includes Ubrelvy side ...
Banophen
Banophen is used for allergic reactions, allergic rhinitis, cold symptoms, cough, extrapyramidal ...
Benadryl Allergy
Benadryl Allergy is used for allergic reactions, allergic rhinitis, allergies, cold symptoms ...
Pseudoephedrine/triprolidine
Pseudoephedrine/triprolidine systemic is used for allergic rhinitis, cold symptoms
Echinacea
Echinacea systemic is used for cold symptoms, condylomata acuminata, herbal supplementation
Chlorpheniramine
Chlorpheniramine systemic is used for allergic reactions, allergic rhinitis, allergies, cold ...
Diphenhydramine
Diphenhydramine is an antihistamine used to treat sneezing, runny nose, itching, hives and other ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.