Acetaminophen/dextromethorphan/doxylamine/guaifenesin/phenylephrine Interactions
There are 667 drugs known to interact with acetaminophen/dextromethorphan/doxylamine/guaifenesin/phenylephrine, along with 15 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 102 are major, 551 are moderate, and 14 are minor.
- View all 667 medications that may interact with acetaminophen/dextromethorphan/doxylamine/guaifenesin/phenylephrine
- View acetaminophen/dextromethorphan/doxylamine/guaifenesin/phenylephrine alcohol/food interactions (2)
- View acetaminophen/dextromethorphan/doxylamine/guaifenesin/phenylephrine disease interactions (15)
Most frequently checked interactions
View interaction reports for acetaminophen / dextromethorphan / doxylamine / guaifenesin / phenylephrine and the medicines listed below.
- Benadryl (diphenhydramine)
- Biofreeze (menthol topical)
- BuSpar (buspirone)
- CoQ10 (ubiquinone)
- Durezol (difluprednate ophthalmic)
- Eliquis (apixaban)
- Evusheld (cilgavimab / tixagevimab)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flomax (tamsulosin)
- Flonase (fluticasone nasal)
- Ginkgo Biloba (ginkgo)
- Lagevrio (molnupiravir)
- Lasix (furosemide)
- Lunesta (eszopiclone)
- Metoprolol Succinate ER (metoprolol)
- Mounjaro (tirzepatide)
- Paxil (paroxetine)
- Prevnar 20 (pneumococcal 20-valent conjugate vaccine)
- Protonix (pantoprazole)
- Valerian Root (valerian)
- Xanax (alprazolam)
- Xarelto (rivaroxaban)
- Zinc (zinc sulfate)
- ZzzQuil (diphenhydramine)
Acetaminophen/dextromethorphan/doxylamine/guaifenesin/phenylephrine alcohol/food interactions
There are 2 alcohol/food interactions with acetaminophen / dextromethorphan / doxylamine / guaifenesin / phenylephrine.
Acetaminophen/dextromethorphan/doxylamine/guaifenesin/phenylephrine disease interactions
There are 15 disease interactions with acetaminophen / dextromethorphan / doxylamine / guaifenesin / phenylephrine which include:
- alcoholism
- liver disease
- depression
- cardiovascular disease
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- BPH
- diabetes
- glaucoma
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Benadryl
Benadryl is an antihistamine and is used to treat sneezing, runny nose, itching and other ...
Promethazine DM
Promethazine DM is used for allergic rhinitis, cold symptoms, cough
Ubrelvy
Ubrelvy (ubrogepant) tablets are used for the acute treatment of migraine. Includes Ubrelvy side ...
Banophen
Banophen is used for allergic reactions, allergic rhinitis, cold symptoms, cough, extrapyramidal ...
Benadryl Allergy
Benadryl Allergy is used for allergic reactions, allergic rhinitis, allergies, cold symptoms ...
Pseudoephedrine/triprolidine
Pseudoephedrine/triprolidine systemic is used for allergic rhinitis, cold symptoms
Echinacea
Echinacea systemic is used for cold symptoms, condylomata acuminata, herbal supplementation
Chlorpheniramine
Chlorpheniramine systemic is used for allergic reactions, allergic rhinitis, allergies, cold ...
Diphenhydramine
Diphenhydramine is an antihistamine used to treat sneezing, runny nose, itching, hives and other ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.