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Margesic (acetaminophen / butalbital / caffeine) Drug Interactions

A total of 1039 drugs are known to interact with Margesic (acetaminophen / butalbital / caffeine).

  • 216 major drug interactions
  • 714 moderate drug interactions
  • 109 minor drug interactions

Show all medications in the database that may interact with Margesic (acetaminophen / butalbital / caffeine).

Check for interactions

Type in a drug name to check for interactions with Margesic (acetaminophen / butalbital / caffeine).

Most frequently checked interactions

View interaction reports for Margesic (acetaminophen / butalbital / caffeine) and the medicines listed below.

  • atenolol (Tenormin)
  • atorvastatin (Lipitor)
  • bupropion (Wellbutrin, Wellbutrin XL, Wellbutrin SR, Zyban, Buproban, Aplenzin, Budeprion, Forfivo XL, Budeprion SR, Budeprion XL)
  • carbamazepine (Tegretol, Carbatrol, Tegretol XR, Epitol, Equetro, Carnexiv)
  • escitalopram (Lexapro)
  • hydrocodone (Hysingla ER, Zohydro ER, Vantrela ER)
  • hyoscyamine (Levsin, Hyosyne, Levbid, Anaspaz, Levsin SL, Cystospaz, Oscimin, Levsinex SR, HyoMax, Symax Duotab, Levsinex, HyoMax SL, NuLev, Gastrosed, Cystospaz-M, Symax SL, A-Spas S/L, Donnamar, Hyosol, IB-Stat, Hyospaz, Ed-Spaz, Spasdel, HyoMax DT, Symax FasTab, A-Spaz, Symax SR, Colidrops, HyoMax FT, HyoMax SR)
  • Imodium Multi-Symptom Relief (loperamide / simethicone)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • melatonin (Melatonin Time Release, SGard, Bio-Melatonin, Health Aid Melatonin, VesPro Melatonin)
  • prednisone (Deltasone, Rayos, Sterapred, Prednicot, Meticorten, Sterapred DS, Liquid Pred, Orasone, Prednicen-M)
  • sertraline (Zoloft)

Margesic (acetaminophen / butalbital / caffeine) alcohol/food interactions

There are 6 alcohol/food interactions with Margesic (acetaminophen / butalbital / caffeine)

Margesic (acetaminophen / butalbital / caffeine) disease interactions

There are 23 disease interactions with Margesic (acetaminophen / butalbital / caffeine) which include:

More about Margesic (acetaminophen / butalbital / caffeine)

Related treatment guides

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.