Skip to Content

Margesic (acetaminophen / butalbital / caffeine) Drug Interactions

A total of 1035 drugs are known to interact with Margesic (acetaminophen / butalbital / caffeine).

  • 215 major drug interactions
  • 712 moderate drug interactions
  • 108 minor drug interactions

Show all medications in the database that may interact with Margesic (acetaminophen / butalbital / caffeine).

Check for interactions with Margesic (acetaminophen / butalbital / caffeine)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Margesic (acetaminophen / butalbital / caffeine)

  • atenolol (Tenormin)
  • atorvastatin (Lipitor)
  • bupropion (Wellbutrin, Wellbutrin XL, Wellbutrin SR, Zyban, Buproban, Budeprion, Aplenzin, Forfivo XL, Budeprion SR, Budeprion XL)
  • carbamazepine (Tegretol, Carbatrol, Tegretol XR, Epitol, Equetro, Carnexiv)
  • escitalopram (Lexapro)
  • hydrocodone (Hysingla ER, Zohydro ER, Vantrela ER)
  • hyoscyamine (Levsin, Hyosyne, Levbid, Levsin SL, Anaspaz, NuLev, Cystospaz, Oscimin, HyoMax, Symax Duotab, Symax SR, Symax FasTab, Gastrosed, Cystospaz-M, Levsinex SR, Symax SL, A-Spas S/L, Donnamar, Hyosol, IB-Stat, Hyospaz, Ed-Spaz, Spasdel, Levsinex, HyoMax DT, A-Spaz, Colidrops, HyoMax FT, HyoMax SL, HyoMax SR)
  • Imodium Multi-Symptom Relief (loperamide / simethicone)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • melatonin (Melatonin Time Release, Bio-Melatonin, SGard, Health Aid Melatonin, VesPro Melatonin)
  • prednisone (Deltasone, Rayos, Sterapred, Sterapred DS, Prednicot, Meticorten, Orasone, Liquid Pred, Prednicen-M)
  • sertraline (Zoloft)

Margesic (acetaminophen / butalbital / caffeine) alcohol/food interactions

There are 6 alcohol/food interactions with Margesic (acetaminophen / butalbital / caffeine)

Margesic (acetaminophen / butalbital / caffeine) disease interactions

There are 23 disease interactions with Margesic (acetaminophen / butalbital / caffeine) which include:

More about Margesic (acetaminophen / butalbital / caffeine)

Related treatment guides

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.