What are VEGF/VEGFR inhibitors?
Vascular endothelial growth factor (VEGF)/ vascular endothelial growth factor receptor (VEGFR) inhibitors are agents that inhibit the activity of VEGF and VEGFR. VEGR and VEGFR (a tyrosine kinase receptor) signaling modulates angiogenesis, which involves making of new blood vessels from existing blood vessels.
Abnormal angiogenesis is known to occur in cancer, degenerative eye conditions and other conditions that involve inflammation. Specific monoclonal antibodies can be used as VEGF inhibitors and particular tyrosine kinase inhibitors are used as VEGFR inhibitors.
Vascular endothelial growth factor (VEGF)/ vascular endothelial growth factor receptor (VEGFR) inhibitors are used to treat various types of cancers.
List of VEGF/VEGFR inhibitors:
|Drug Name||Reviews||Avg. Ratings|
|ziv-aflibercept systemic (Pro)||1 review||10|
|bevacizumab systemic (Pro)||30 reviews||8.2|
|pazopanib systemic (Pro)||82 reviews||8.2|
|lenvatinib systemic (Pro)||2 reviews||7.5|
|sunitinib systemic (Pro)||32 reviews||6.9|
|axitinib systemic (Pro)||1 review||6.0|
|sorafenib systemic (Pro)||15 reviews||5.6|
|cabozantinib systemic (Pro)||11 reviews||5.5|
|regorafenib systemic (Pro)||4 reviews||4.0|
|ponatinib systemic (Pro)||2 reviews||3.0|
|ramucirumab systemic (Pro)||0 reviews||Add rating|
|vandetanib systemic (Pro)||0 reviews||Add rating|
|For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).|
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical conditions associated with VEGF/VEGFR inhibitors:
- Acute Lymphoblastic Leukemia
- Cervical Cancer
- Chronic Myelogenous Leukemia
- Colorectal Cancer
- Endometrial Cancer
- Fallopian Tube Cancer
- Gastric Cancer
- Gastrointestinal Stromal Tumor
- Glioblastoma Multiforme
- Hepatic Tumor
- Hepatocellular Carcinoma
- Non-Small Cell Lung Cancer
- Ovarian Cancer
- Pancreatic Cancer
- Peritoneal Cancer
- Renal Cell Carcinoma
- Soft Tissue Sarcoma
- Stomach Cancer
- Thyroid Cancer