SGLT-2 inhibitors
Other names: SGLT2 inhibitors, sodium-glucose cotransporter-2 inhibitors
What are SGLT-2 inhibitors?
SGLT-2 inhibitor is an abbreviation for sodium-glucose cotransporter-2 inhibitors. SGLT-2 inhibitors are a class of medicine used to lower high blood glucose levels in people with type 2 diabetes. They may also be called gliflozins.
SGLT-2 inhibitors inhibit SGLT-2 proteins located in the renal tubules of the kidneys which are responsible for reabsorbing glucose back into the blood. As a result, more glucose is excreted in the urine. SGLT-2 inhibitors have been shown to be effective at lowering hemoglobin A1c levels, improving weight loss and lowering blood pressure. They carry a low risk of hypoglycemia (low blood sugar levels).
They are usually well tolerated. SGLT-2 inhibitors may be used in the treatment of type 2 diabetes and act independently of beta-cell function in the pancreas.
List of SGLT-2 inhibitors
| Drug Name | Avg. Rating | Reviews |
|---|---|---|
| Jardiance (Pro) Generic name: empagliflozin |
328 reviews | |
| Invokana (Pro) Generic name: canagliflozin |
257 reviews | |
| Farxiga (Pro) Generic name: dapagliflozin |
164 reviews | |
| Steglatro (Pro) Generic name: ertugliflozin |
11 reviews | |
| Brenzavvy (Pro) Generic name: bexagliflozin |
1 review | |
| Inpefa (Pro) Generic name: sotagliflozin | No reviews | |
| For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective). | ||
See also
Medical conditions treated or associated with SGLT-2 inhibitors:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.