Tonmya Dosage

Recommended Dosage

The recommended dosage of TONMYA is 5.6 mg administered sublingually once daily at bedtime:

• Starting dose: Days 1 to 14, administer 2.8 mg (1 sublingual tablet) once daily at bedtime.
• Target dose: Days 15 and thereafter, administer 5.6 mg (2 sublingual tablets) once daily at bedtime.
• Maximum recommended dosage: 5.6 mg once daily.

Recommended Dosage in Geriatric Patients

The recommended TONMYA dosage―and the maximum recommended dosage―in geriatric patients is 2.8 mg administered sublingually once daily at bedtime.

Recommended Dosage in Patients with Hepatic Impairment

The recommended TONMYA dosage―and the maximum recommended dosage―in patients with mild hepatic impairment is 2.8 mg administered sublingually once daily at bedtime. TONMYA is not recommended in patients with moderate or severe hepatic impairment.

Administration Instructions

TONMYA is only for sublingual use.

• Administer after brushing teeth and finishing other oral care and ensure a moist mouth/sublingual area by drinking a few sips of water prior to administration.
• Place the sublingual tablet(s) under the tongue until dissolved.
• Do not swallow whole, cut, crush, or chew.
• Avoid eating or drinking for at least 15 minutes after the sublingual tablet(s) has/have completely dissolved at bedtime and preferably avoid any hot, cold, or acidic beverages until the morning.
• Avoid talking for at least 5 minutes after administration.

Recommendations Regarding Missed Dose(s)

If you missed a TONMYA bedtime dose, take TONMYA the next evening. Do not take a missed dose during the day.

Pregnancy Testing Prior to Administration

Pregnancy testing is recommended in females of reproductive potential prior to initiating treatment with TONMYA